公开(公告)号：US11377440B2

公开(公告)日：2022-07-05

申请号：US16652221

申请日：2018-10-04

申请人： GlaxoSmithKline Intellectual Property Development Limited

发明人： David T. Fosbenner ,  Todd L. Graybill ,  Jianxing Kang ,  Bryan W. King ,  Yunfeng Lan ,  Lara Kathryn Leister ,  Mukesh K. Mahajan ,  John F. Mehlmann ,  Angel I. Morales-Ramos ,  George Scott Pesiridis ,  Joshi M. Ramanjulu ,  Joseph J. Romano ,  Stuart Paul Romeril ,  Mark J. Schulz ,  Huiqiang Zhou ,  Junya Qu

IPC分类号： C07D403/14 ,  C07D401/14 ,  C07D405/14

摘要： Disclosed are compounds having the formula: (I) wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, R17, Rx, and Ry are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.