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公开(公告)号:US20180030134A1
公开(公告)日:2018-02-01
申请号:US15788433
申请日:2017-10-19
申请人: Genzyme Corporation
发明人: Yunxiang Zhu , Jozsef Karman , Ronnie Wei , Canwen Jiang , Seng Cheng
IPC分类号: C07K16/28 , C07K14/47 , C07K14/705 , C07K14/74
摘要: The present invention provides a bispecific biologic comprising a ligand specific for CTLA-4 and a ligand specific for a pMHC complex.
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公开(公告)号:US20210380686A1
公开(公告)日:2021-12-09
申请号:US17306509
申请日:2021-05-03
申请人: Genzyme Corporation
发明人: Yunxiang Zhu , Jozsef Karman , Ronnie Wei , Canwen Jiang , Seng Cheng
IPC分类号: C07K16/28 , C07K14/74 , C07K14/47 , C07K14/705
摘要: The present invention provides a bispecific biologic comprising a ligand specific for CTLA-4 and a ligand specific for a pMHC complex.
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公开(公告)号:US12043665B2
公开(公告)日:2024-07-23
申请号:US17306509
申请日:2021-05-03
申请人: Genzyme Corporation
发明人: Yunxiang Zhu , Jozsef Karman , Ronnie Wei , Canwen Jiang , Seng Cheng
IPC分类号: C07K16/28 , A61K38/17 , A61K39/395 , A61P37/06 , C07K14/47 , C07K14/705 , C07K14/74
CPC分类号: C07K16/2803 , C07K14/47 , C07K14/70532 , C07K14/70539 , C07K2319/00
摘要: The present invention provides a bispecific biologic comprising a ligand specific for CTLA-4 and a ligand specific for a pMHC complex.
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公开(公告)号:US11028170B2
公开(公告)日:2021-06-08
申请号:US15788433
申请日:2017-10-19
申请人: Genzyme Corporation
发明人: Yunxiang Zhu , Jozsef Karman , Ronnie Wei , Canwen Jiang , Seng Cheng
IPC分类号: C07K14/47 , C07K14/705 , C07K19/00 , A61K38/17 , A61K39/395 , C07K16/28 , C07K14/74
摘要: The present invention provides a bispecific biologic comprising a ligand specific for CTLA-4 and a ligand specific for a pMHC complex.
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