公开(公告)号：US20210371889A1

公开(公告)日：2021-12-02

申请号：US17350690

申请日：2021-06-17

Applicant: Genomatica, Inc.

Inventor： Derek L. GREENFIELD ,  Louis G. HOM ,  Fernando A. SANCHEZ-RIERA ,  Zhihao HU ,  Vikranth ARLAGADDA ,  Eli S. GROBAN ,  Scott A. FRYKMAN

IPC: C12P7/64 ,  C07K14/245 ,  C07K14/195 ,  C07C31/125 ,  C07C33/02 ,  C07C53/126

Abstract: The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, and engineered host cells for producing fatty acids and derivates of fatty acids such as acyl-CoA, terminal olefins, fatty aldehydes, fatty alcohols, alkanes, alkenes, wax esters, ketones and internal olefins through altered expression of the transcription factor, fadR.