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公开(公告)号:US12016862B2
公开(公告)日:2024-06-25
申请号:US17524050
申请日:2021-11-11
申请人: Genentech, Inc.
发明人: Marie Evangelista , Mark Andrew Merchant , Jennifer Lee Schutzman , Ting-Kun Mark Lin , Stephanie Royer Joo , Sandhya Vinayak Mandlekar , Stuart G. Lutzker
IPC分类号: A61P35/00 , A61K31/517 , C07D487/14 , C07K16/22
CPC分类号: A61K31/517 , A61P35/00 , C07K16/22
摘要: Provided herein are combination therapies comprising a KRasG12C inhibitor (e.g. Compound 1 or a pharmaceutically acceptable salt thereof) and a VEGF antagonist (e.g., bevacizumab) and methods of using such combination therapies.
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公开(公告)号:US20220152030A1
公开(公告)日:2022-05-19
申请号:US17524050
申请日:2021-11-11
申请人: Genentech, Inc.
发明人: Marie Evangelista , Mark Andrew Merchant , Jennifer Lee Schutzman , Ting-Kun Mark Lin , Stephanie Royer Joo , Sandhya Vinayak Mandlekar , Stuart G. Lutzker
IPC分类号: A61K31/517 , A61P35/00 , C07K16/22
摘要: Provided herein are combination therapies comprising a KRasG12C inhibitor (e.g. Compound 1 or a pharmaceutically acceptable salt thereof) and a VEGF antagonist (e.g., bevacizumab) and methods of using such combination therapies.
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