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公开(公告)号：US20230330249A1
公开(公告)日：2023-10-19
申请号：US18156744
申请日：2023-01-19
Applicant: Genentech, Inc.
Inventor： Peter Scott DRAGOVICH , Summer A. BAKER DOCKREY , Thomas Harden PILLOW , Donglu ZHANG
CPC classification number: A61K47/6811 , A61P35/00
Abstract: The subject matter described herein is directed to antibody-CIDE conjugates (Ab-CIDEs) that target BRM for degradation, to pharmaceutical compositions containing them, and to their use in treating diseases and conditions where BRM degradation is beneficial.
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