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公开(公告)号:US20240085404A1
公开(公告)日:2024-03-14
申请号:US18486325
申请日:2023-10-13
Applicant: Genentech, Inc.
Inventor: Chang LIU , John Hok Nin LOWE , Shan CHUNG
CPC classification number: G01N33/5044 , G01N33/6854 , G01N2333/70535
Abstract: The present disclosure relates to methods and compositions useful for measuring the transcytosis or recycling of a molecule. In particular, the present disclosure relates to in vitro receptor-dependent transcytosis or recycling assays for evaluating the clearance rates of therapeutic antibody molecules and Fc-fusion proteins in humans and animals.
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公开(公告)号:US20210172932A1
公开(公告)日:2021-06-10
申请号:US17177414
申请日:2021-02-17
Applicant: GENENTECH, INC.
Inventor: Shan CHUNG , Van Hong NGUYEN , An SONG
Abstract: The present disclosure relates to methods and compositions useful for measuring the transcytosis of a molecule. In particular, the present disclosure relates to in vitro receptor-dependent transcytosis assays for evaluating the clearance rates of therapeutic antibody molecules and Fc-fusion proteins in humans and animals.
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