公开(公告)号：US20230295145A1

公开(公告)日：2023-09-21

申请号：US18323240

申请日：2023-05-24

Applicant: Genentech, Inc.

Inventor： Jakob Fuhrmann ,  Nicholas John Skelton ,  Peter Scott Dragovich

IPC: C07D413/14 ,  C07D417/14 ,  C07D403/12 ,  C07D405/14 ,  C07D409/14 ,  C07D401/14 ,  C07D487/04 ,  A61P35/00

CPC classification number: C07D413/14 ,  C07D417/14 ,  C07D403/12 ,  C07D405/14 ,  C07D409/14 ,  C07D401/14 ,  C07D487/04 ,  A61P35/00

Abstract: The present disclosure relates to compounds and pharmaceutical compositions thereof, and methods of using the compounds and compositions in therapy, such as methods of treating cancer.

公开(公告)号：US12187816B2

公开(公告)日：2025-01-07

申请号：US17355022

申请日：2021-06-22

Applicant: Genentech, Inc.

Inventor： Jakob Fuhrmann ,  Wayne Fairbrother ,  Hao Wu ,  Jeremy Murray

IPC: C07K7/64 ,  A61K31/551 ,  A61K38/00 ,  A61K47/64

Abstract: Provided, inter alia, are macrocyclic compounds.