公开(公告)号：US20130195870A1

公开(公告)日：2013-08-01

申请号：US13694413

申请日：2012-11-29

Applicant: Genentech, Inc.

Inventor： Bijay Shankar Jaiswal ,  Somasekar Seshagiri

IPC: C12Q1/68 ,  A61K39/395 ,  A61K31/517

CPC classification number: C12Q1/6886 ,  A61K31/517 ,  A61K39/39558 ,  C12Q2600/112 ,  C12Q2600/156

Abstract: The present invention concerns somatic ErbB3 mutations in cancer including methods of identifying, diagnosing, and prognosing ErbB3 cancers, as well as methods of treating cancer, including certain subpopulations of patients.

Abstract translation: 本发明涉及癌症中的体细胞ErbB3突变，包括鉴定，诊断和预测ErbB3癌症的方法，以及治疗癌症的方法，包括患者的某些亚群。