公开(公告)号：US20220306726A1

公开(公告)日：2022-09-29

申请号：US17544796

申请日：2021-12-07

Applicant: Genentech, Inc.

Inventor： Amit Mehta

IPC: C07K16/06 ,  C07K1/36 ,  C07K1/18 ,  C07K1/34

Abstract: The present invention relates to the field of protein purification. In particular, the invention concerns methods for increasing the filtration capacity of virus filters, by combined use of endotoxin removal and cation-exchange media in the prefiltration process.

公开(公告)号：US20140301977A1

公开(公告)日：2014-10-09

申请号：US14355818

申请日：2012-11-02

Applicant: Genentech, Inc.

Inventor： Deepa Nadarajah ,  Amit Mehta

IPC: C07K1/22 ,  C07K16/00

CPC classification number: C07K16/00 ,  B01D15/14 ,  B01D15/327 ,  B01D15/363 ,  B01D15/3804 ,  B01D15/3847 ,  B01D15/424 ,  C07K1/16 ,  C07K1/165 ,  C07K1/18 ,  C07K1/22

Abstract: The present invention provides methods for purifying a polypeptide from a composition comprising the polypeptide and at least one contaminant by overloading a chromatography material and eluting the product.

Abstract translation: 本发明提供了通过过载色谱材料并洗脱产物从包含多肽和至少一种污染物的组合物中纯化多肽的方法。

公开(公告)号：US11225513B2

公开(公告)日：2022-01-18

申请号：US16848564

申请日：2020-04-14

Applicant: Genentech, Inc.

Inventor： Amit Mehta

IPC: C07K1/36 ,  C07K1/18 ,  C07K1/34 ,  C07K16/06

Abstract: The present invention relates to the field of protein purification. In particular, the invention concerns methods for increasing the filtration capacity of virus filters, by combined use of endotoxin removal and cation-exchange media in the prefiltration process.