公开(公告)号：US09725459B2

公开(公告)日：2017-08-08

申请号：US14693987

申请日：2015-04-23

申请人： GRÜNENTHAL GMBH

发明人： Antonio Nardi ,  Paul Ratcliffe ,  Tobias Craan ,  Torsten Hertrampf ,  Bernhard Lesch ,  Robert Kime ,  Henning Steinhagen

IPC分类号： C07D491/048

CPC分类号： C07D491/048

摘要： The invention relates to amidic oxotetrahydro-2H-furo[3.2-b]pyrrol-4(5H)-yl) derivatives as dual CatS/K inhibitors. to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.