公开(公告)号：US20200215003A1

公开(公告)日：2020-07-09

申请号：US16818275

申请日：2020-03-13

Applicant: GRÜNENTHAL GMBH

Inventor： Thomas CHRISTOPH ,  Sabine Karine Katrien INGHELBRECHT ,  Roger Carolus Augusta EMBRECHTS ,  Ulrich REINHOLD ,  Marc SCHILLER ,  Eva WULSTEN ,  Petra BLOMS-FUNKE ,  Klaus SCHIENE ,  Ulrich FEIL

IPC: A61K31/135 ,  A61K31/137 ,  A61K45/06 ,  A61K9/00

Abstract: An aqueous pharmaceutical composition adapted for parenteral administration of tapentadol or a physiologically acceptable salt thereof having a pH value of at least 5.4.

公开(公告)号：US20170273970A1

公开(公告)日：2017-09-28

申请号：US15622292

申请日：2017-06-14

Applicant: GRÜNENTHAL GMBH

Inventor： Petra BLOMS-FUNKE ,  Gregor Bahrenberg ,  Wolfgang Schröder ,  Sven Kühnert ,  Simon Lucas

IPC: A61K31/47

CPC classification number: A61K31/47 ,  A61K31/4704

Abstract: The invention relates to certain compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders that are, at least partially, mediated by TSPO activity.