公开(公告)号：US20230270757A1

公开(公告)日：2023-08-31

申请号：US18007020

申请日：2021-07-27

申请人： GNT PHARMA CO., LTD.

发明人： Weiqiang ZHAN ,  Zhanguo WANG ,  Wei ZHANG ,  Lingyan FU ,  Qian LIN ,  Xiaoli CHEN ,  Guoyang LV ,  Liyin ZHONG ,  Xinliang XU ,  Fangmeng ZHU

IPC分类号： A61K31/606 ,  A61K9/19 ,  A61K9/00

CPC分类号： A61K31/606 ,  A61K9/19 ,  A61K9/0019

摘要： A salfaprodil freeze-dried powder injection, and a preparation method thereof and the use thereof are proposed. The preparation method may include adding salfaprodil into water for injection, filtering after the salfaprodil is completely dissolved, and adjusting pH of filtrate with an alkaline substance water solution. The method may also include adding the injection water to achieve a constant volume, filling with an inert gas for protection, and performing sterilization and filtration to obtain a salfaprodil solution, which is then freeze-dried to obtain the -salfaprodil freeze-dried powder injection.