公开(公告)号：US11371061B2

公开(公告)日：2022-06-28

申请号：US15772902

申请日：2016-11-30

Applicant: GENETHON ,  INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) ,  UNIVERSITE D'EVRY VAL D'ESSONNE

Inventor： Saliha Majdoul ,  David Fenard

IPC: C12N15/87 ,  C12N15/86 ,  C07K14/82 ,  A61K48/00 ,  C07K14/47

Abstract: The present invention relates to peptides and compositions for use in improving transduction efficiency of viruses into target cells.

公开(公告)号：US10465169B2

公开(公告)日：2019-11-05

申请号：US15105880

申请日：2014-12-17

Applicant: GENETHON

Inventor： Driss Boudeffa ,  Otto-Wilhelm Merten ,  David Fenard

IPC: C07K16/24 ,  A61K39/395 ,  C07K16/00 ,  C12N15/113 ,  A61K39/00 ,  C12N7/00 ,  C12N15/86

Abstract: The invention relates to a process for purifying enveloped viruses. The process of the invention is useful for recovering at a large scale enveloped viruses under conditions complying with good manufacturing practices and allowing viruses of a clinical grade to be obtained.

公开(公告)号：US10125352B2

公开(公告)日：2018-11-13

申请号：US15022049

申请日：2014-09-12

Applicant: GENETHON

Inventor： David Fenard

IPC: A61K39/00 ,  C12N7/00 ,  C07K14/005 ,  A61K39/12 ,  A01N63/00 ,  C12N15/86

Abstract: The invention relates to a process for producing enveloped viruses in a mildly acid medium. The processes of the invention are useful for producing and recovering at a large scale enveloped viruses under conditions observing good manufacturing practice (GMP).