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公开(公告)号:US20220099677A1
公开(公告)日:2022-03-31
申请号:US17469533
申请日:2021-09-08
Applicant: GENENTECH, INC.
Inventor: Vinita GUPTA , Ann Therese BRADY , James Thomas KOERBER , Xiangdan WANG , Minh Michael Nhu PHAN , Yonglian SUN
IPC: G01N33/574
Abstract: The present disclosure provides assays for the detection and/or quantification of membrane-associated proteins, e.g., circulating CD20 (cCD20), incorporating an extracellular vesicle-based calibrator comprising the membrane-associated tumor antigen as well as the use of such assays in the detection and treatment of hyperproliferative disorders.