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公开(公告)号:US20180016325A1
公开(公告)日:2018-01-18
申请号:US15718876
申请日:2017-09-28
申请人: Genentech, Inc.
发明人: Eric J. Brown , Martine Darwish , John Flygare , Wouter Hazenbos , Byoung Chul Lee , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC分类号: C07K16/12 , A61K45/06 , A61K39/40 , A61K31/4025 , A61K31/5386
CPC分类号: C07K16/1271 , A61K31/4025 , A61K31/5386 , A61K39/40 , A61K45/06 , A61K47/6809 , A61K47/6835 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
摘要: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
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公开(公告)号:US20160074529A1
公开(公告)日:2016-03-17
申请号:US14945716
申请日:2015-11-19
申请人: GENENTECH, INC.
发明人: Eric J. Brown , John Flygare , Wouter Hazenbos , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC分类号: A61K47/48 , A61K31/7048 , A61K31/4709 , A61K38/12 , A61K31/4375 , A61K31/4436 , A61K31/7056 , A61K31/439
CPC分类号: A61K47/6849 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , A61K31/4709 , A61K31/7048 , A61K31/7056 , A61K38/12 , A61K47/6801 , A61K47/6803 , A61K47/6809 , A61K47/6835 , A61K47/6851 , C07K16/1271 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
摘要: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
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公开(公告)号:US10570192B2
公开(公告)日:2020-02-25
申请号:US15718876
申请日:2017-09-28
申请人: Genentech, Inc.
发明人: Eric J. Brown , Martine Darwish , John Flygare , Wouter Hazenbos , Byoung Chul Lee , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC分类号: C07K16/12 , A61K39/40 , A61K31/5386 , A61K45/06 , A61K31/4025 , A61K47/68
摘要: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
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公开(公告)号:US20150366985A1
公开(公告)日:2015-12-24
申请号:US14284619
申请日:2014-05-22
申请人: GENENTECH, INC.
发明人: Eric J. Brown , John Flygare , Wouter Hazenbos , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC分类号: A61K47/48 , A61K31/395
CPC分类号: A61K47/6849 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , A61K31/4709 , A61K31/7048 , A61K31/7056 , A61K38/12 , A61K47/6801 , A61K47/6803 , A61K47/6809 , A61K47/6835 , A61K47/6851 , C07K16/1271 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
摘要: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
摘要翻译: 本发明提供了抗壁磷壁酸抗体及其抗生素缀合物及其使用方法。
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公开(公告)号:US20140356375A1
公开(公告)日:2014-12-04
申请号:US14284609
申请日:2014-05-22
申请人: GENENTECH, INC.
发明人: Eric J. Brown , Martine Darwish , John Flygare , Wouter Hazenbos , Byoung Chul Lee , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC分类号: C07K16/12 , A61K39/40 , A61K31/5383 , A61K47/48
CPC分类号: C07K16/1271 , A61K31/5383 , A61K47/6809 , A61K47/6835 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
摘要: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
摘要翻译: 本发明提供了抗壁磷壁酸抗体及其抗生素缀合物及其使用方法。
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公开(公告)号:US20180125995A1
公开(公告)日:2018-05-10
申请号:US15612193
申请日:2017-06-02
申请人: Genentech, Inc.
发明人: Eric Brown , Wouter Hazenbos , Isidro Hotzel , Kimberly Kajihara , Sophie M. Lehar , Sanjeev Mariathasan , Thomas Pillow , Leanna Staben , Vishal Verma , Binqing Wei , Yi Xia , Min Xu
IPC分类号: A61K47/68 , C07K16/12 , A61K31/5383 , A61K45/06 , A61P31/04
CPC分类号: A61K47/6803 , A61K31/5383 , A61K45/06 , A61K47/6835 , A61K47/6889 , A61P31/04 , C07K16/1271 , C07K2317/21
摘要: The invention provides rF1 antibody antibiotic conjugates and methods of using same.
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公开(公告)号:US09884126B2
公开(公告)日:2018-02-06
申请号:US14284619
申请日:2014-05-22
申请人: Genentech, Inc.
发明人: Eric J. Brown , John Flygare , Wouter Hazenbos , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC分类号: A61K47/48 , C07K16/12 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , A61K31/4709 , A61K31/7048 , A61K31/7056 , A61K38/12
CPC分类号: A61K47/6849 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , A61K31/4709 , A61K31/7048 , A61K31/7056 , A61K38/12 , A61K47/6801 , A61K47/6803 , A61K47/6809 , A61K47/6835 , A61K47/6851 , C07K16/1271 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
摘要: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
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公开(公告)号:US20180021450A1
公开(公告)日:2018-01-25
申请号:US15611985
申请日:2017-06-02
申请人: Genentech, Inc.
发明人: Eric Brown , Wouter Hazenbos , Isidro Hotzel , Kimberly Kajihara , Sophie M. Lehar , Sanjeev Mariathasan , Thomas Pillow , Leanna Staben , Vishal Verma , Binqing Wei , Min Xu
IPC分类号: A61K47/68 , A61K31/4468 , A61K39/40 , A61K31/496
CPC分类号: A61K47/6809 , A61K31/4468 , A61K31/496 , A61K39/40 , A61K47/6803 , A61K47/6835 , A61K47/6889
摘要: The invention provides anti-Staphylococcus aureus antibody rifamycin antibiotic conjugates and methods of using same.
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公开(公告)号:US20180085470A1
公开(公告)日:2018-03-29
申请号:US15834740
申请日:2017-12-07
申请人: Genentech, Inc.
发明人: Eric J. Brown , John Flygare , Wouter Hazenbos , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC分类号: A61K31/7056 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , C07K16/12 , A61K38/12 , A61K31/7048 , A61K31/4709
CPC分类号: A61K47/6849 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , A61K31/4709 , A61K31/7048 , A61K31/7056 , A61K38/12 , A61K47/6801 , A61K47/6803 , A61K47/6809 , A61K47/6835 , A61K47/6851 , C07K16/1271 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
摘要: The invention provides anti-wall teichoic acid antibodies, antibiotic-linker intermediates, and antibody-antibiotic conjugate compound, and methods of making and using the same.
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公开(公告)号:US09895450B2
公开(公告)日:2018-02-20
申请号:US14945716
申请日:2015-11-19
申请人: Genentech, Inc.
发明人: Eric J. Brown , John Flygare , Wouter Hazenbos , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC分类号: A61K39/395 , A61K47/48 , C07K16/12 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , A61K31/4709 , A61K31/7048 , A61K31/7056 , A61K38/12
CPC分类号: A61K47/6849 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , A61K31/4709 , A61K31/7048 , A61K31/7056 , A61K38/12 , A61K47/6801 , A61K47/6803 , A61K47/6809 , A61K47/6835 , A61K47/6851 , C07K16/1271 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
摘要: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
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