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公开(公告)号:US20040044179A1
公开(公告)日:2004-03-04
申请号:US10219535
申请日:2002-08-14
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Luc Desnoyers , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean-Philippe F. Stephan , Colin K. Watanabe , William I. Wood
IPC: C12P021/02 , C12N005/06 , C07K014/47 , C07H021/04 , C12N009/00
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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2.
公开(公告)号:US20030224984A1
公开(公告)日:2003-12-04
申请号:US10305654
申请日:2002-11-26
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Napoleone Ferrara , Hans-Peter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Kenneth J. Hillan , Scot A. Marsters , James Pan , Nicholas F. Paoni , Jean-Philippe F. Stephan , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Weilan Ye
IPC: A61K038/17 , C07K014/47 , C07K016/18 , C12P021/02 , C12N005/06 , C07H021/04 , C12N009/00
CPC classification number: C07K16/22 , A61K38/00 , A61K2039/505 , C07K14/515
Abstract: Compositions and methods are disclosed for stimulating or inhibiting angiogenesis and/or cardiovascularization in mammals, including humans. Pharmaceutical compositions are based on polypeptides or antagonists thereto that have been identified for one or more of these uses. Disorders that can be diagnosed, prevented, or treated by the compositions herein include trauma such as wounds, various cancers, and disorders of the vessels including atherosclerosis and cardiac hypertrophy. In addition, the present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030187211A1
公开(公告)日:2003-10-02
申请号:US10219525
申请日:2002-08-13
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Luc Desnoyers , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean-Philippe F. Stephan , Colin K. Watanabe , William I. Wood
IPC: C12P021/02 , C12N005/06 , C07K014/47 , C07H021/04 , C12N009/00
CPC classification number: C07K14/705 , C07K14/47 , G01N33/574
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030187210A1
公开(公告)日:2003-10-02
申请号:US10219483
申请日:2002-08-13
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Luc Desnoyers , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean-Philippe F. Stephan , Colin K. Watanabe , William I. Wood
IPC: C12P021/02 , C12N005/06 , C07K014/47 , C07H021/04 , C12N009/00
CPC classification number: C07K14/705 , C07K14/47 , G01N33/574
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030105289A1
公开(公告)日:2003-06-05
申请号:US10219472
申请日:2002-08-13
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Luc Desnoyers , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean-Philippe F. Stephan , Colin K. Watanabe , William I. Wood
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
CPC classification number: C07K14/705 , C07K14/47 , G01N33/574
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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6.
公开(公告)号:US20030105013A1
公开(公告)日:2003-06-05
申请号:US10223090
申请日:2002-08-16
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Napoleone Ferrara , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Kenneth J. Hillan , Scot A. Marsters , James Pan , Jean-Philippe F. Stephan , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Weilan Ye
IPC: A61K038/17 , C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
CPC classification number: A61K38/17 , C07H21/04 , C07K14/435 , C07K14/47 , C12N5/06 , C12N9/00 , C12P21/02
Abstract: Compositions and methods are disclosed for stimulating or inhibiting angiogenesis and/or cardiovascularization in mammals, including humans. Pharmaceutical compositions are based on polypeptides or antagonists thereto that have been identified for one or more of these uses. Disorders that can be diagnosed, prevented, or treated by the compositions herein include trauma such as wounds, various cancers, and disorders of the vessels including atherosclerosis and cardiac hypertrophy. In addition, the present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030100735A1
公开(公告)日:2003-05-29
申请号:US10230433
申请日:2002-08-28
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Luc Desnoyers , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean-Philippe F. Stephan , Colin K. Watanabe , William I. Wood
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
CPC classification number: C07K14/705 , C07K14/47 , G01N33/574
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030100734A1
公开(公告)日:2003-05-29
申请号:US10230427
申请日:2002-08-28
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Luc Desnoyers , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean-Philippe F. Stephan , Colin K. Watanabe , William I. Wood
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
CPC classification number: C07K14/705 , C07K14/47 , G01N33/574
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030100732A1
公开(公告)日:2003-05-29
申请号:US10230306
申请日:2002-08-28
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Luc Desnoyers , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean-Philippe F. Stephan , Colin K. Watanabe , William I. Wood
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
CPC classification number: C07K14/705 , C07K14/47 , G01N33/574
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030100723A1
公开(公告)日:2003-05-29
申请号:US10219482
申请日:2002-08-13
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Luc Desnoyers , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean-Philippe F. Stephan , Colin K. Watanabe , William I. Wood
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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