Saved successfully
Save failed
Saved Successfully
Save Failed
公开(公告)号:US20140037618A1
公开(公告)日:2014-02-06
申请号:US13902714
申请日:2013-05-24
Applicant: GENENTECH, INC.
Inventor: Svetlana Pidasheva , Hilary Clark , Nico P. Ghilardi , Timothy W. Behrens , Hergen Spits , Sara Trifari
IPC: G01N33/68 , C12Q1/68
CPC classification number: G01N33/6872 , C12Q1/6883 , C12Q2600/106 , C12Q2600/156
Abstract: The present invention relates to compositions and methods of diagnosing and treating autoimmune and inflammatory disorders that are characterized by IL-23R loss-of-function mutations.
Abstract translation: 本发明涉及以IL-23R功能丧失突变为特征的诊断和治疗自身免疫性和炎症性疾病的组合物和方法。