公开(公告)号：US20230084248A1

公开(公告)日：2023-03-16

申请号：US17795848

申请日：2021-01-28

Applicant: GENCURIX INC.

Inventor： Sang Rae CHO ,  Young Ho MOON ,  Jinil HAN

IPC: C12Q1/6886

Abstract: The present invention relates to a composition, a kit, a nucleic acid, and a method capable of diagnosing bladder cancer by detecting the methylation level of a CpG site of at least one gene selected from the group consisting of IFFO1, MARCH11, BARHL2, NR2E1, KCNA3, and BOLL. According to the present invention, since the hypermethylation of a CpG site of a gene is specifically exhibited in bladder cancer, a composition, a kit, a chip, or a method according to the present invention can be used to accurately and rapidly diagnose bladder cancer and to be used for early diagnosis and monitoring recurrence.

公开(公告)号：US20230383356A1

公开(公告)日：2023-11-30

申请号：US18030515

申请日：2021-10-08

Applicant: GENCURIX INC.

Inventor： Sang Rae CHO ,  Young Ho MOON ,  Jinil HAN ,  Yun Young LEE ,  Joon AN

IPC: C12Q1/6886

CPC classification number: C12Q1/6886 ,  C12Q2600/154

Abstract: The present invention relates to a composition, a kit, a nucleic acid chip and a method, for diagnosing colorectal cancer, rectal cancer or colorectal adenoma by detecting the methylation level of CpG sites in a LINC01798 gene, in which colorectal cancer, rectal cancer, or colorectal adenoma can not only be diagnosed accurately and rapidly, but can also be diagnosed early.

公开(公告)号：US20240352537A1

公开(公告)日：2024-10-24

申请号：US18761983

申请日：2024-07-02

Applicant: GENCURIX INC.

Inventor： Sang Rae CHO ,  Young Ho MOON ,  Jinil HAN ,  Yun Young LEE

IPC: C12Q1/6886 ,  C12Q1/6851

CPC classification number: C12Q1/6886 ,  C12Q1/6851 ,  C12Q2600/154

Abstract: The present invention relates to a composition, a kit, a nucleic acid chip, and a method which make it possible to diagnose prostate cancer by detecting the methylation level of CpG sites of one or more genes selected from the group consisting of KLK4, HES5, TPM4, MOB3B, NNT, IL17RD, DTX4, NOL3, ADD3, EXT1, CPED1, and C2orf88, thus enabling an accurate and rapid diagnosis of prostate cancer, as well as the early diagnosis thereof.

公开(公告)号：US20230132750A1

公开(公告)日：2023-05-04

申请号：US17995685

申请日：2021-04-08

Applicant: GENCURIX INC.

Inventor： Sang Rae CHO ,  Young Ho MOON ,  Jinil HAN ,  Yun Young LEE

IPC: C12Q1/6886

Abstract: The present invention relates to a composition, a kit, a nucleic acid chip, and a method capable of diagnosing colorectal cancer, rectal cancer, or colorectal adenoma by detecting the methylation level of CpG sites in a GLRB gene. Accordingly, colorectal cancer, rectal cancer, or colorectal adenoma can be diagnosed not only accurately and quickly, but also at an early stage.