Process for preparing 2,3-dihydroxybenzoic acid amides of
tetraazaalkanes and cycloalkanes
    1.
    发明授权
    Process for preparing 2,3-dihydroxybenzoic acid amides of tetraazaalkanes and cycloalkanes 失效
    制备四氮杂烷烃和环烷烃的2,3-二羟基苯甲酸酰胺的方法

    公开(公告)号:US4543213A

    公开(公告)日:1985-09-24

    申请号:US64593

    申请日:1979-08-07

    IPC分类号: C07D257/02

    CPC分类号: C07D257/02

    摘要: A compound of the formula: ##STR1## wherein X is hydrogen or a conventional electron-withdrawing group, particularly --SO.sub.3 H or a salt thereof; n is 2, 3, or 4; m is 2, 3, or 4; and p is 2 or 3. The present compounds are useful as specific sequestering agents for actinide (IV) ions. Also described is a method for the 2,3-dihydroxybenzamidation of azaalkanes.

    摘要翻译: 下式的化合物:其中X为氢或常规吸电子基团,特别是-SO 3 H或其盐; n为2,3或4; m为2,3或4; 并且p为2或3.本发明化合物可用作锕系元素(IV)离子的特定螯合剂。 还描述了氮杂烷烃的2,3-二羟基苯甲酰胺化方法。

    2,3-Dihydroxybenzoic acid amides of tetraazaalkanes and tetaaza
cycloalkanes
    2.
    发明授权
    2,3-Dihydroxybenzoic acid amides of tetraazaalkanes and tetaaza cycloalkanes 失效
    四氮杂烷烃和四氮杂环烷烃的2,3-二羟基苯甲酸酰胺

    公开(公告)号:US4181654A

    公开(公告)日:1980-01-01

    申请号:US927234

    申请日:1978-07-24

    IPC分类号: C07D257/02 C07C103/87

    CPC分类号: C07D257/02

    摘要: A compound of the formula: ##STR1## wherein X is hydrogen or a conventional electron-withdrawing group, particularly --SO.sub.3 H or a salt thereof; n is 2, 3, or 4; m is 2, 3, or 4; and p is 2 or 3. The present compounds are useful as specific sequestering agents for actinide (IV) ions. Also described is a method for the 2,3-dihydroxybenzamidation of azaalkanes.

    摘要翻译: 下式的化合物:其中X是氢或常规吸电子基团,特别是-SO 3 H或其盐; n为2,3或4; m为2,3或4; 并且p为2或3.本发明化合物可用作锕系元素(IV)离子的特定螯合剂。 还描述了氮杂烷烃的2,3-二羟基苯甲酰胺化方法。

    Polycatecholamide chelating agents
    3.
    发明授权
    Polycatecholamide chelating agents 失效
    聚儿茶酚胺螯合剂

    公开(公告)号:US4442305A

    公开(公告)日:1984-04-10

    申请号:US295512

    申请日:1981-08-24

    IPC分类号: C07C65/03 C07C101/72

    CPC分类号: C07C65/03 Y10S514/836

    摘要: Novel polybenzamide compounds useful for in vitro or in vivo chelation are described. The compounds have the formula ##STR1## Polyamines are reacted with 2,3-dimethoxy benzoyl chloride unsubstituted or substituted with SO.sub.3 H, SO.sub.3 M, NO.sub.2, CO.sub.2 H or CO.sub.2 M as desired is reacted with a polyamine in an inert solvent then demethylated with BBr.sub.3 or BCl.sub.3 in an inert solvent. Where compounds symmetrically substituted on the terminal N's are desired, the polyamine is first reductively alkylated by reaction with an aldehyde or ketone and the resulting Schiff base is hydrogenated.

    摘要翻译: 描述了可用于体外或体内螯合的新型聚苯甲酰胺化合物。 所述化合物具有下式:将多胺与未被取代或被SO 3 H,SO 3 M,NO 2,CO 2 H或CO 2 M取代的2,3-二甲氧基苯甲酰氯反应,根据需要,在惰性溶剂中与多胺反应,然后用BBr 3或BCl 3脱甲基 惰性溶剂。 当需要在末端N上对称取代的化合物时,首先通过与醛或酮反应将多胺还原烷基化,并将所得希夫碱氢化。

    In vitro removal of actinide (IV) ions
    4.
    发明授权
    In vitro removal of actinide (IV) ions 失效
    体外去除锕系元素(Ⅳ)离子

    公开(公告)号:US4309305A

    公开(公告)日:1982-01-05

    申请号:US64596

    申请日:1979-08-07

    IPC分类号: C07D257/02 G21F9/04

    CPC分类号: C07D257/02

    摘要: A compound of the formula: ##STR1## wherein X is hydrogen or a conventional electron-withdrawing group, particularly --SO.sub.3 H or a salt thereof; n is 2, 3, or 4; m is 2, 3, or 4; and p is 2 or 3. The present compounds are useful as specific sequestering agents for actinide (IV) ions. Also described is a method for the 2,3-dihydroxybenzamidation of azaalkanes.

    摘要翻译: 下式的化合物:其中X是氢或常规吸电子基团,特别是-SO 3 H或其盐; n为2,3或4; m为2,3或4; 并且p为2或3.本发明化合物可用作锕系元素(IV)离子的特定螯合剂。 还描述了氮杂烷烃的2,3-二羟基苯甲酰胺化方法。