公开(公告)号：US11666635B2

公开(公告)日：2023-06-06

申请号：US17020279

申请日：2020-09-14

申请人： Ferring B.V.

发明人： Helen Ulrika Sjögren ,  Charlotte Hojer-Pedersen

IPC分类号： A61K38/24 ,  A61K9/00 ,  A61K47/18 ,  A61K9/08 ,  A61P15/08 ,  A61K47/10 ,  A61K47/26

CPC分类号： A61K38/24 ,  A61K9/0019 ,  A61K9/08 ,  A61K47/10 ,  A61K47/183 ,  A61K47/26 ,  A61P15/08

摘要： The present invention pertains in general to the field of the stabilization of gonadotropin formulations, in particular liquid formulations of gonadotropins. The stabilization is achieved by a particular combination of excipients, preferably arginine and methionine. In a preferred embodiment, the formulation does not comprise a buffer.

公开(公告)号：US20210236600A1

公开(公告)日：2021-08-05

申请号：US17020279

申请日：2020-09-14

申请人： Ferring B.V.

发明人： Helen Ulrika Sjögren ,  Charlotte Hojer-Pedersen

IPC分类号： A61K38/24 ,  A61K9/00 ,  A61K47/18 ,  A61K9/08 ,  A61P15/08 ,  A61K47/10 ,  A61K47/26

摘要： The present invention pertains in general to the field of the stabilization of gonadotropin formulations, in particular liquid formulations of gonadotropins. The stabilization is achieved by a particular combination of excipients, preferably arginine and methionine. In a preferred embodiment, the formulation does not comprise a buffer.