公开(公告)号：US07570054B1

公开(公告)日：2009-08-04

申请号：US12114326

申请日：2008-05-02

Applicant: Fa-Hsuan Lin

Inventor： Fa-Hsuan Lin

IPC: G01V3/00

CPC classification number: G01R33/5611 ,  G01R33/34084 ,  G01R33/3415 ,  G01R33/4806 ,  G01R33/4824 ,  G01R33/5602 ,  G01R33/5608 ,  G01R33/5616 ,  G01R33/56308

Abstract: An fMRI scan is performed using a multi-element head coil and multi-channel receiver to acquire time course image data. One imaging gradient is eliminated from the pulse sequence used to acquire the time course image data enabling images to be acquired at a very high frame rate. The multi-channel NMR data is combined and reconstructed into a series of image frames using a spatial filter calculated using a linear constrained minimum variance (LCMV) beamforming method.

Abstract translation: 使用多元素头线圈和多通道接收器执行fMRI扫描以获取时间过程图像数据。 从用于获取时间图像数据的脉冲序列中消除一个成像梯度，使得以非常高的帧速率获取图像。 使用使用线性约束最小方差（LCMV）波束成形方法计算的空间滤波器将多通道NMR数据组合并重构成一系列图像帧。

公开(公告)号：US20110241673A1

公开(公告)日：2011-10-06

申请号：US12753555

申请日：2010-04-02

Applicant: Fa-Hsuan Lin

Inventor： Fa-Hsuan Lin

IPC: G01R33/48

CPC classification number: G01R33/5611

Abstract: A method for producing an image of a subject with a magnetic resonance imaging (MRI) system is provided. In particular, spatial encoding of signals received from the subject is performed by spatial encoding magnetic fields (SEMs) produced by driving a parallel array of local gradient coils with current weightings that define a mode of the coil array. A set of globally orthogonal modes are determined using a singular value decomposition and two modes that produce SEMs with desired magnetic field variance characteristics are selected for spatial encoding. The spatially encoding signals are received by a parallel array of radio frequency receiver coil elements in order to resolve ambiguities in spatial encoding caused by the SEMs. Images are subsequently reconstructed using, for example, an iterative time domain reconstruction method.

Abstract translation: 提供了一种用于产生具有磁共振成像（MRI）系统的对象的图像的方法。 特别地，通过对通过限定线圈阵列的模式的当前加权驱动局部梯度线圈的并行阵列产生的磁场（SEM）来执行从对象接收的信号的空间编码。 使用奇异值分解确定一组全局正交模式，并选择产生具有期望磁场方差特征的SEM的两种模式进行空间编码。 空间编码信号由射频接收器线圈元件的并联阵列接收，以便解决由SEM引起的空间编码中的歧义。 随后使用例如迭代时域重建方法重建图像。

公开(公告)号：US20090179643A1

公开(公告)日：2009-07-16

申请号：US12114326

申请日：2008-05-02

Applicant: Fa-Hsuan Lin

Inventor： Fa-Hsuan Lin

IPC: G01R33/54

CPC classification number: G01R33/5611 ,  G01R33/34084 ,  G01R33/3415 ,  G01R33/4806 ,  G01R33/4824 ,  G01R33/5602 ,  G01R33/5608 ,  G01R33/5616 ,  G01R33/56308

Abstract: An fMRI scan is performed using a multi-element head coil and multi-channel receiver to acquire time course image data. One imaging gradient is eliminated from the pulse sequence used to acquire the time course image data enabling images to be acquired at a very high frame rate. The multi-channel NMR data is combined and reconstructed into a series of image frames using a spatial filter calculated using a linear constrained minimum variance (LCMV) beamforming method.

Abstract translation: 使用多元素头线圈和多通道接收器执行fMRI扫描以获取时间过程图像数据。 从用于获取时间图像数据的脉冲序列中消除一个成像梯度，使得以非常高的帧速率获取图像。 使用使用线性约束最小方差（LCMV）波束成形方法计算的空间滤波器将多通道NMR数据组合并重构成一系列图像帧。

公开(公告)号：US20080272782A1

公开(公告)日：2008-11-06

申请号：US12114339

申请日：2008-05-02

Applicant: Fa-Hsuan Lin

Inventor： Fa-Hsuan Lin

IPC: G01R33/54

CPC classification number: G01R33/485 ,  G01R33/4806 ,  G01R33/482 ,  G01R33/4824 ,  G01R33/4838 ,  G01R33/5607 ,  G01R33/561 ,  G01R33/5616 ,  G01R33/565 ,  G01R33/56545

Abstract: A method for suppressing the noise component of a measured magnetic resonance (MR) signal is disclosed. In particular, a signal-space projection operator is produced and employed to suppress the noise component from acquired MR signals that is uncorrelated with the spatial pattern of a desired NMR signal. In one embodiment, an fMRI scan is performed to acquire time course image data. The NMR data is filtered with a signal-space projection operator and reconstructed into a series of image frames. In another embodiment, the signal-space projection operator is employed to suppress lipid signal in MRS image data.

Abstract translation: 公开了一种用于抑制测量的磁共振（MR）信号的噪声分量的方法。 特别地，产生信号空间投影算子并且用于抑制与所需NMR信号的空间图案不相关的所获取的MR信号的噪声分量。 在一个实施例中，执行fMRI扫描以获取时间过程图像数据。 NMR数据用信号空间投影算子滤波并重构成一系列图像帧。 在另一个实施例中，采用信号空间投影算子来抑制MRS图像数据中的脂质信号。

公开(公告)号：US09329251B2

公开(公告)日：2016-05-03

申请号：US13463847

申请日：2012-05-04

Applicant: Fa-Hsuan Lin

Inventor： Fa-Hsuan Lin

IPC: G01R33/483

CPC classification number: G01R33/483

Abstract: This invention provides a multi-dimensional encoded (MDE) magnetic resonance imaging (MRI) scheme to map a q-dimensional object with p spatial encoding magnetic fields (SEMs) onto a p-dimensional space where p is equal to or larger than q. The provided MDE MRI scheme links imaging schemes using linear and nonlinear gradients. The present invention also provides a system and method of optimizing the spatial bases in MDE MRI. With a higher dimension encoding space in MDE MRI, the image can be reconstructed in a more efficiency and accurate manner.

Abstract translation: 本发明提供了一种多维编码（MDE）磁共振成像（MRI）方案，用于将q维对象与p空间编码磁场（SEM）映射到p等于或大于q的p维空间上。 提供的MDE MRI方案使用线性和非线性梯度链接成像方案。 本发明还提供了一种优化MDE MRI中的空间基础的系统和方法。 在MDE MRI中具有更高维度的编码空间，可以以更高效和准确的方式重建图像。

公开(公告)号：US20110254549A1

公开(公告)日：2011-10-20

申请号：US12762922

申请日：2010-04-19

Applicant: Fa-Hsuan Lin

Inventor： Fa-Hsuan Lin

IPC: G01R33/48

CPC classification number: G01R33/5611

Abstract: A method for parallel magnetic resonance imaging (“pMRI”) that does not require the explicit estimation of a coil sensitivity map is provided. Individual coil images are reconstructed from undersampled scan data that is acquired with a radio frequency (RF) coil array having multiple coil channels. An inverse operator is formed from autocalibration scan (ACS) data, and is applied to the acquired scan data in order to produce reconstruction coefficients. Missing k-space lines in the undersampled scan data are synthesized by interpolating k-space lines in the acquired scan data using the reconstruction coefficients. From the acquired scan data and the synthesized missing k-space lines, individual coil images are reconstructed and combined to form an image of the subject.

Abstract translation: 提供了不需要明确估计线圈灵敏度映射的并行磁共振成像（“pMRI”）的方法。 使用由具有多个线圈通道的射频（RF）线圈阵列获取的欠采样扫描数据来重建各个线圈图像。 逆运算符由自动校准扫描（ACS）数据形成，并被应用于获取的扫描数据，以产生重构系数。 欠采样扫描数据中缺少的k空间线通过使用重建系数内插所获取的扫描数据中的k空间线来合成。 从获取的扫描数据和合成的缺失的k空间线中，重建和组合单个线圈图像以形成被摄体的图像。

公开(公告)号：US07394252B1

公开(公告)日：2008-07-01

申请号：US11743739

申请日：2007-05-03

Applicant: Fa-Hsuan Lin

Inventor： Fa-Hsuan Lin

IPC: G01V3/00

CPC classification number: G01R33/5611 ,  G01R33/5608

Abstract: The invention relates to a method for reconstructing a fully sampled k-space data set. An undersampled GRAPPA scan of a subject is performed in a parallel MRI system using a set of receiver coil elements and corresponding receiver channels to obtain a reduced k-space data set. Autocalibration samples in k-space for each receiver channel are obtained and a GRAPPA reconstruction kernel β is calculated from the reduced k-space data set and autocalibration samples. Missing k-space lines are reconstructed to obtain a reconstructed k-space data set which together with the reduced k-space data set fully samples each channel of k-space. Each line is reconstructed using a regularized GRAPPA reconstruction if prior k-space information is available and using an unregularized GRAPPA reconstruction if no prior k-space information is available. The regularized GRAPPA reconstructions are performed preferably using a Tikhonov regularization framework.

Abstract translation: 本发明涉及一种用于重构完全采样的k空间数据集的方法。 使用一组接收器线圈元件和相应的接收器通道在并行MRI系统中执行被摄体的欠采样GRAPPA扫描以获得减小的k空间数据集。 获得每个接收器通道的k空间中的自动校准样本，并从减少的k空间数据集和自动校准样本计算出GRAPPA重建核心β。 重建缺失k空间线以获得重建的k空间数据集，其与缩小的k空间数据集一起完全采样k空间的每个信道。 如果先前的k空间信息可用，并且如果没有先前的k空间信息可用，则使用未规则化的GRAPPA重构，使用正则化的GRAPPA重构来重构每一行。 正则化的GRAPPA重建优选地使用Tikhonov正则化框架来执行。

公开(公告)号：US20050270024A1

公开(公告)日：2005-12-08

申请号：US10859348

申请日：2004-06-03

Applicant: Fa-Hsuan Lin

Inventor： Fa-Hsuan Lin

IPC: G01R33/561 ,  G01V3/00

CPC classification number: G01R33/5611

Abstract: The invention relates to a method of parallel imaging reconstruction in parallel magnetic resonance imaging reconstruction. Magnetic resonance data is acquired in parallel by an array of separate RF receiver coils. A reconstruction method based on Tikhonov regularization is presented to reduce the SNR loss due to geometric correlations in the spatial information from the array coil elements. In order to reduce the noise amplification of the reconstruction so-called “g-factor”, reference scans are utilized as a priori information of the final reconstructed image to provide regularized estimates for the reconstruction using the L-curve technique. According to the invention the method with the proposed L-curve approach was fully automatic and showed a significant reduction in average g-factors in the experimental_images.

Abstract translation: 本发明涉及一种并行成像重建在平行磁共振成像重建中的方法。 磁共振数据由独立的RF接收器线圈阵列并行获取。 提出了一种基于Tikhonov正则化的重建方法，以减少由于阵列线圈元件的空间信息中几何相关的SNR损失。 为了减少重建所谓的“g因子”的噪声放大，使用参考扫描作为最终重建图像的先验信息，以使用L曲线技术为重建提供正则化估计。 根据本发明，提出的L曲线方法的方法是完全自动的，并且在实验图像中平均g因子显着降低。

公开(公告)号：US20130293229A1

公开(公告)日：2013-11-07

申请号：US13463847

申请日：2012-05-04

Applicant: Fa-Hsuan Lin

Inventor： Fa-Hsuan Lin

IPC: G01R33/48

CPC classification number: G01R33/483

Abstract: This invention provides a multi-dimensional encoded (MDE) magnetic resonance imaging (MRI) scheme to map a q-dimensional object with p spatial encoding magnetic fields (SEMs) onto a p-dimensional space where p is equal to or larger than q. The provided MDE MRI scheme links imaging schemes using linear and nonlinear gradients. The present invention also provides a system and method of optimizing the spatial bases in MDE MRI. With a higher dimension encoding space in MDE MRI, the image can be reconstructed in a more efficiency and accurate manner.

Abstract translation: 本发明提供了一种多维编码（MDE）磁共振成像（MRI）方案，用于将q维对象与p空间编码磁场（SEM）映射到p等于或大于q的p维空间上。 提供的MDE MRI方案使用线性和非线性梯度链接成像方案。 本发明还提供了一种优化MDE MRI中的空间基础的系统和方法。 在MDE MRI中具有更高维度的编码空间，可以以更高效和准确的方式重建图像。

公开(公告)号：US08400152B2

公开(公告)日：2013-03-19

申请号：US12762922

申请日：2010-04-19

Applicant: Fa-Hsuan Lin

Inventor： Fa-Hsuan Lin

IPC: G01V3/00

CPC classification number: G01R33/5611

Abstract: A method for parallel magnetic resonance imaging (“pMRI”) that does not require the explicit estimation of a coil sensitivity map is provided. Individual coil images are reconstructed from undersampled scan data that is acquired with a radio frequency (RF) coil array having multiple coil channels. An inverse operator is formed from autocalibration scan (ACS) data, and is applied to the acquired scan data in order to produce reconstruction coefficients. Missing k-space lines in the undersampled scan data are synthesized by interpolating k-space lines in the acquired scan data using the reconstruction coefficients. From the acquired scan data and the synthesized missing k-space lines, individual coil images are reconstructed and combined to form an image of the subject.

Abstract translation: 提供了不需要明确估计线圈灵敏度映射的并行磁共振成像（pMRI）的方法。 使用由具有多个线圈通道的射频（RF）线圈阵列获取的欠采样扫描数据来重建各个线圈图像。 逆运算符由自动校准扫描（ACS）数据形成，并被应用于获取的扫描数据，以产生重构系数。 欠采样扫描数据中缺少的k空间线通过使用重建系数内插所获取的扫描数据中的k空间线来合成。 从获取的扫描数据和合成的缺失的k空间线中，重建和组合单个线圈图像以形成被摄体的图像。