公开(公告)号：US20230023174A1

公开(公告)日：2023-01-26

申请号：US17773800

申请日：2020-11-11

Applicant: FIVE PRIME THERAPEUTICS, INC.

Inventor： Hong XIANG ,  Siddhartha MITRA

IPC: C07K14/705 ,  A61P35/00

Abstract: The present disclosure provides methods of administering fusion proteins comprising the extracellular domain of human cluster of differentiation 80 (CD80) and the fragment crystallizable (Fc) domain of human immunoglobulin G1 (IgG1) to a subject in need thereof, for example, a cancer patient.

公开(公告)号：US20230382972A9

公开(公告)日：2023-11-30

申请号：US17773800

申请日：2020-11-04

Applicant: FIVE PRIME THERAPEUTICS, INC.

Inventor： Hong XIANG ,  Siddhartha MITRA

IPC: C07K14/705 ,  A61P35/00

CPC classification number: C07K14/70532 ,  A61P35/00 ,  A61K2039/505

Abstract: The present disclosure provides methods of administering fusion proteins comprising the extracellular domain of human cluster of differentiation 80 (CD80) and the fragment crystallizable (Fc) domain of human immunoglobulin G1 (IgG1) to a subject in need thereof, for example, a cancer patient.

公开(公告)号：US20240228578A1

公开(公告)日：2024-07-11

申请号：US17904928

申请日：2021-02-26

Applicant: Five Prime Therapeutics, Inc.

Inventor： Siddhartha MITRA ,  Maike SCHMIDT ,  Kathleen M. SULLIVAN

IPC: C07K14/705 ,  A61K38/00 ,  A61K39/00 ,  A61P35/00 ,  C07K16/28

CPC classification number: C07K14/70532 ,  A61P35/00 ,  C07K16/2818 ,  A61K38/00 ,  A61K2039/505 ,  A61K2039/545 ,  C07K2317/41 ,  C07K2319/30

Abstract: The present disclosure provides methods of administering fusion proteins comprising the extracellular domain of human cluster of differentiation 80 (CD80) and the fragment crystallizable (Fc) domain of human immunoglobulin G 1 (IgG1), optionally in combination with a PD-1/PD-L1 antagonist, to a subject in need thereof, for example, a cancer patient.