公开(公告)号：US20230072079A1

公开(公告)日：2023-03-09

申请号：US17786631

申请日：2020-12-18

Applicant: Evaxion Biotech A/S

Inventor： Birgitte Rønø ,  Jens Kringelum ,  Anders Bundgård Sørensen ,  Thomas Trolle ,  Stine Friis

IPC: A61K39/00 ,  C12N15/117 ,  C12N15/85 ,  A61K39/39 ,  A61P35/00

Abstract: Products and methods for DNA vaccination targeting cancer. A method for anti-cancer vaccination using a plasmid-based vaccine comprising regions encoding neo-epitopes.

公开(公告)号：US20230147574A1

公开(公告)日：2023-05-11

申请号：US17995601

申请日：2021-04-07

Applicant: Evaxion Biotech A/S

Inventor： Birgitte Rønø ,  Marina Barrio Calvo ,  Anders Bundgård Sørensen ,  Christian Thygesen ,  Jens Kringelum ,  Stine Friis

IPC: C07K14/74 ,  A61K39/00 ,  C12N15/62 ,  A61K39/39 ,  A61P35/00 ,  C07K14/52 ,  C07K16/28 ,  C07K14/78 ,  C07K14/47

CPC classification number: C07K14/70539 ,  A61K39/0011 ,  C12N15/62 ,  A61K39/39 ,  A61P35/00 ,  C07K14/521 ,  C07K16/2851 ,  C07K14/78 ,  A61K39/001151 ,  C07K14/4746 ,  A61K39/001196 ,  C07K2319/33 ,  A61K2039/505 ,  A61K38/00

Abstract: The present invention relates to cancer therapy, in particular cancer immunotherapy. In particular, the present invention relates to methods and products for treating cancer by administration of specific fusion polypeptides or nucleic acids encoding such fusion polypeptides.

公开(公告)号：US20220184191A1

公开(公告)日：2022-06-16

申请号：US17437940

申请日：2020-03-11

Applicant: Evaxion Biotech A/S

Inventor： Birgitte Rønø ,  Jens Kringelum ,  Anders Bundgård Sørensen ,  Thomas Trolle

IPC: A61K39/00 ,  A61K39/39

Abstract: Compositions and methods for DNA vaccination that target cancer. The method for anti-cancer vaccination using a plasmid based vaccine comprises regions encoding neo-epitopes and comprising amphiphilic block copolymers such as poloxamer and poloxamine agents.

公开(公告)号：US20230355733A1

公开(公告)日：2023-11-09

申请号：US18004889

申请日：2021-07-14

Applicant: Evaxion Biotech A/S

Inventor： Birgitte Rønø ,  Marina Barrio Calvo ,  Anders Bundgård Sørensen ,  Christian Thygesen ,  Jens Kringelum ,  Stine Friis

IPC: A61K39/00 ,  A61K39/215 ,  A61P37/04

CPC classification number: A61K39/001121 ,  A61K39/215 ,  A61P37/04 ,  A61K2039/627 ,  A61K2039/70

Abstract: Immune therapy and vaccines, such as cancer immunotherapy, or vaccines for infections with microorganisms, such as a bacterial or viral infection. In particular, the present invention relates to methods and products for prophylactic or treating cancer or infections with microorganisms by administration of specific fusion polypeptides or nucleic acids encoding such fusion polypeptides.