公开(公告)号：US20180161461A1

公开(公告)日：2018-06-14

申请号：US15877042

申请日：2018-01-22

Applicant: Ecole Polytechnique

Inventor： Markus Schoeffel ,  Antigoni Alexandrou ,  Cedric Bouzigues ,  Thierry Gacoin ,  Jean-Pierre Boilot

IPC: A61K49/18 ,  A61K49/00

CPC classification number: A61K49/1824 ,  A61K49/0002 ,  B82Y5/00 ,  B82Y15/00 ,  C09K11/7794

Abstract: The present application concerns multimodal composite products for imaging, in particular for diagnostic imaging, and optionally for therapy, in particular composite products which are capable of being used as contrast agents, in particular in magnetic resonance imaging (MRI), and/or in imaging techniques such as, for example, in optical imaging, in the optical detection of oxidants, in positron emission tomography (PET), in tomodensitometry (TDM) and/or in ultrasound imaging, and optionally simultaneously for use in therapy. These products are based on a particle comprising or consisting of a portion provided with a contrast agent activity and/or a paramagnetic activity, and a portion provided with a luminescent activity and optionally an oxidant detection activity.

公开(公告)号：US20150010476A1

公开(公告)日：2015-01-08

申请号：US14383859

申请日：2013-03-08

Applicant: Ecole Polytechnique

Inventor： Markus Schoeffel ,  Antigoni Alexandrou ,  Cedric Bouzigues ,  Thierry Gacoin ,  Jean-Pierre Boilot

IPC: A61K49/18

CPC classification number: A61K49/1824 ,  A61K49/0002 ,  B82Y5/00 ,  B82Y15/00 ,  C09K11/7794

Abstract: The present application concerns multimodal composite products for imaging, in particular for diagnostic imaging, and optionally for therapy, in particular composite products which are capable of being used as contrast agents, in particular in magnetic resonance imaging (MRI), and/or in imaging techniques such as, for example, in optical imaging, in the optical detection of oxidants, in positron emission tomography (PET), in tomodensitometry (TDM) and/or in ultrasound imaging, and optionally simultaneously for use in therapy. These products are based on a particle comprising or consisting of a portion provided with a contrast agent activity and/or a paramagnetic activity, and a portion provided with a luminescent activity and optionally an oxidant detection activity.

Abstract translation: 本申请涉及用于成像的多峰复合产品，特别是用于诊断成像，并且可选地用于治疗，特别是能够用作造影剂的复合产品，特别是在磁共振成像（MRI）和/或成像 技术，例如在光学成像，氧化剂的光学检测，正电子发射断层摄影（PET），心律失真测定（TDM）和/或超声成像中的技术，以及可选地同时用于治疗。 这些产品基于包含具有造影剂活性和/或顺磁性活性的部分或由具有发光活性和任选的氧化剂检测活性的部分组成的颗粒。