公开(公告)号：US20220296681A1

公开(公告)日：2022-09-22

申请号：US17633351

申请日：2020-08-06

申请人： Deutsches Krebsforschungszentrum ,  Universität Heidelberg

发明人： Hellmut G. Augustin ,  Corinne Hübers ,  Ashik Ahmed Abdul Pari ,  Martin Petkov ,  Moritz Felcht

IPC分类号： A61K38/18 ,  G01N33/574

摘要： The present invention relates to an N-terminal fragment of an angiopoietin like 4 (ANGPTL4) polypeptide, or a therapeutically active variant thereof, for use in the treatment of cancer in a subject. Moreover, the present invention provides an agent which increases the amount of an N-terminal fragment of an angiopoietin like 4 (ANGPTL4) polypeptide for use in treating cancer. Further, encompassed by the present invention is a method for identifying a candidate compound for the treatment of cancer.