公开(公告)号：US20130060017A1

公开(公告)日：2013-03-07

申请号：US13550055

申请日：2012-07-16

申请人： Dennis ESHIMA ,  Mehmet HUSNU ,  Jim STONE ,  Brian C. KELLEY

发明人： Dennis ESHIMA ,  Mehmet HUSNU ,  Jim STONE ,  Brian C. KELLEY

IPC分类号： C07H1/00

CPC分类号： C07H5/02

摘要： The invention relates to methods for synthesizing compounds on solid supports. The invention also relates to synthesizing labeled compounds, such as those used in the field of radiopharmaceuticals. The invention relates to methods for synthesizing halogenated radiopharmaceuticals such as fludeoxyglucose (also known as fluorodeoxyglucose or FDG).

摘要翻译： 本发明涉及在固体支持物上合成化合物的方法。 本发明还涉及合成标记的化合物，例如在放射性药物领域中使用的化合物。 本发明涉及卤代放射性药物如氟脱氧葡萄糖（也称为氟脱氧葡萄糖或FDG）的合成方法。

公开(公告)号：US20130060134A1

公开(公告)日：2013-03-07

申请号：US13606591

申请日：2012-09-07

申请人： Dennis ESHIMA ,  Mehmet HUSNU ,  Jim STONE

发明人： Dennis ESHIMA ,  Mehmet HUSNU ,  Jim STONE

IPC分类号： G01T1/24 ,  A61B6/04 ,  A61N5/10 ,  G01T1/167

CPC分类号： A61B6/037 ,  A61B6/12 ,  A61B6/4241 ,  A61N5/1049 ,  A61N2005/1052 ,  G01T1/1614

摘要： A tumor treatment apparatus may include an array of collimated CZT detectors configured to intersect a known coordinate and measure gamma radiation activity, for example at 511 keV. A radiation delivery system may be configured to direct radiation through the known coordinate on the basis of the gamma radiation activity. A translatable and rotatable table may be configured to support a tumor host, wherein the tumor is positionable relative to the known coordinate on the basis of the gamma radiation activity emitted by the tumor and measured by the array of collimated CZT detectors. Radiation from the radiation delivery system may be delivered to the tumor at the known coordinate, and may be delivered in an intra-operative surgical environment.

摘要翻译： 肿瘤治疗装置可以包括被配置为与已知坐标相交并且测量γ辐射活动的准直CZT检测器阵列，例如在511keV。 辐射递送系统可以被配置为基于伽马辐射活动来引导辐射通过已知坐标。 可翻译和可旋转的桌子可以被配置为支撑肿瘤宿主，其中根据由肿瘤发射的伽马辐射活动并通过准直的CZT检测器阵列测量的肿瘤可相对于已知坐标定位。 来自辐射递送系统的辐射可以以已知的坐标递送到肿瘤，并且可以在手术中的手术环境中递送。