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1.发明申请Cell migration inhibiting compositions and methods and compositions for treating cancer 失效细胞迁移抑制组合物和治疗癌症的方法和组合物公开(公告)号：US20060128742A1
公开(公告)日：2006-06-15
申请号：US11345132
申请日：2006-02-01
Applicant: David Edwards , Michael Berens , Christian Beaudry
Inventor： David Edwards , Michael Berens , Christian Beaudry
IPC: A61K31/4745
CPC classification number: G01N33/5011 , A61K31/00 , A61K31/192 , A61K31/215 , A61K31/381 , A61K31/4745 , A61K31/549 , A61K38/193 , A61K39/00 , A61K45/06 , G01N2500/10 , A61K2300/00
Abstract: Methods for treating an individual having cancer are provided. The method may include administering a cell migration inhibitor and a chemotherapeutic agent to the individual to inhibit migration of cancer cell. Inhibiting cell migration may increase cell division. In this manner, the cell migration inhibitor and the chemotherapeutic agent in combination may have increased efficacy compared to the chemotherapeutic agent alone due to the increased cell division. The cell migration inhibitor may include any of the inhibitors described herein. For example, the cell migration inhibitor may be an organic molecule having a molecular weight of less than about 700, a monoclonal antibody, or a natural product.
Abstract translation: 提供了治疗患有癌症的个体的方法。 该方法可以包括向个体施用细胞迁移抑制剂和化学治疗剂以抑制癌细胞的迁移。 抑制细胞迁移可能增加细胞分裂。 以这种方式，由于细胞分裂增加，细胞迁移抑制剂和化学治疗剂的组合可能与单独的化学治疗剂相比具有增加的功效。 细胞迁移抑制剂可以包括本文所述的任何抑制剂。 例如，细胞迁移抑制剂可以是分子量小于约700的有机分子，单克隆抗体或天然产物。
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2.发明授权Cell migration inhibiting compositions and methods and compositions for treating cancer 失效细胞迁移抑制组合物和治疗癌症的方法和组合物公开(公告)号：US07700615B2
公开(公告)日：2010-04-20
申请号：US11345132
申请日：2006-02-01
Applicant: David L. Edwards , Michael E. Berens , Christian Beaudry
Inventor： David L. Edwards , Michael E. Berens , Christian Beaudry
CPC classification number: G01N33/5011 , A61K31/00 , A61K31/192 , A61K31/215 , A61K31/381 , A61K31/4745 , A61K31/549 , A61K38/193 , A61K39/00 , A61K45/06 , G01N2500/10 , A61K2300/00
Abstract: Methods for treating an individual having cancer are provided. The method may include administering a cell migration inhibitor and a chemotherapeutic agent to the individual to inhibit migration of cancer cell. Inhibiting cell migration may increase cell division. In this manner, the cell migration inhibitor and the chemotherapeutic agent in combination may have increased efficacy compared to the chemotherapeutic agent alone due to the increased cell division. The cell migration inhibitor may include any of the inhibitors described herein. For example, the cell migration inhibitor may be an organic molecule having a molecular weight of less than about 700, a monoclonal antibody, or a natural product.
Abstract translation: 提供了治疗患有癌症的个体的方法。 该方法可以包括向个体施用细胞迁移抑制剂和化学治疗剂以抑制癌细胞的迁移。 抑制细胞迁移可能增加细胞分裂。 以这种方式，由于细胞分裂增加，细胞迁移抑制剂和化学治疗剂的组合可能与单独的化学治疗剂相比具有增加的功效。 细胞迁移抑制剂可以包括本文所述的任何抑制剂。 例如，细胞迁移抑制剂可以是分子量小于约700的有机分子，单克隆抗体或天然产物。
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公开(公告)号：US07012100B1
公开(公告)日：2006-03-14
申请号：US10161843
申请日：2002-06-04
Applicant: David L. Edwards , Michael E. Berens , Christian Beaudry
Inventor： David L. Edwards , Michael E. Berens , Christian Beaudry
CPC classification number: G01N33/5011 , A61K31/00 , A61K31/192 , A61K31/215 , A61K31/381 , A61K31/4745 , A61K31/549 , A61K38/193 , A61K39/00 , A61K45/06 , G01N2500/10 , A61K2300/00
Abstract: Methods for treating an individual having cancer are provided. The method may include administering a cell migration inhibitor and a chemotherapeutic agent to the individual to inhibit migration of cancer cell. Inhibiting cell migration may increase cell division. In this manner, the cell migration inhibitor and the chemotherapeutic agent in combination may have increased efficacy compared to the chemotherapeutic agent alone due to the increased cell division. The cell migration inhibitor may include any of the inhibitors described herein. For example, the cell migration inhibitor may be an organic molecule having a molecular weight of less than about 700, a monoclonal antibody, or a natural product.
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