公开(公告)号：US11117859B1

公开(公告)日：2021-09-14

申请号：US17175575

申请日：2021-02-12

申请人： Dan Yang ,  Jingyi Li ,  Liang Xin ,  Qianqian Zhao ,  Liang Qi ,  Bin Tian ,  Jian Zha ,  Wenbo Yao ,  Gennian Mao ,  Han Li ,  Chunyang Shi ,  Yongbo Wang ,  Jingwen Xu

发明人： Dan Yang ,  Jingyi Li ,  Liang Xin ,  Qianqian Zhao ,  Liang Qi ,  Bin Tian ,  Jian Zha ,  Wenbo Yao ,  Gennian Mao ,  Han Li ,  Chunyang Shi ,  Yongbo Wang ,  Jingwen Xu

IPC分类号： C07C231/24 ,  C07C233/83 ,  C07C231/12

摘要： A compound with anti-drug resistant bacteria activity having the following formula (I) is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

公开(公告)号：US10766885B1

公开(公告)日：2020-09-08

申请号：US16871333

申请日：2020-05-11

申请人： Xingke Ju ,  Chengyuan Liang ,  Bin Tian ,  Yuzhi Liu ,  Lei Tian ,  Gennian Mao ,  Limei Wang ,  Yuanyuan He ,  Yongbo Wang ,  Jingwen Xu ,  Dan Yang ,  Liang Qi ,  Wenbo Yao ,  Qianqian Zhao ,  Han Li

发明人： Xingke Ju ,  Chengyuan Liang ,  Bin Tian ,  Yuzhi Liu ,  Lei Tian ,  Gennian Mao ,  Limei Wang ,  Yuanyuan He ,  Yongbo Wang ,  Jingwen Xu ,  Dan Yang ,  Liang Qi ,  Wenbo Yao ,  Qianqian Zhao ,  Han Li

IPC分类号： C07D407/14 ,  B01J31/02

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US11306076B2

公开(公告)日：2022-04-19

申请号：US16871354

申请日：2020-05-11

申请人： Yonghong Tang ,  Huafeng Qi ,  Peiyu Zhou ,  Xingke Ju ,  Chengyuan Liang ,  Yuzhi Liu ,  Bin Tian ,  Lei Tian ,  Gennian Mao ,  Limei Wang ,  Yuanyuan He ,  Yongbo Wang ,  Jingwen Xu ,  Dan Yang ,  Liang Qi ,  Wenbo Yao ,  Qianqian Zhao ,  Han Li

发明人： Yonghong Tang ,  Huafeng Qi ,  Peiyu Zhou ,  Xingke Ju ,  Chengyuan Liang ,  Yuzhi Liu ,  Bin Tian ,  Lei Tian ,  Gennian Mao ,  Limei Wang ,  Yuanyuan He ,  Yongbo Wang ,  Jingwen Xu ,  Dan Yang ,  Liang Qi ,  Wenbo Yao ,  Qianqian Zhao ,  Han Li

IPC分类号： C07D409/14 ,  B01J27/24

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US11510905B1

公开(公告)日：2022-11-29

申请号：US17239583

申请日：2021-04-24

申请人： Chengyuan Liang ,  Wenjing Yang ,  Qianqian Zhao ,  Liang Xin ,  Jingyi Li ,  Dan Yang ,  Ruina Bian ,  Jie Zhang ,  Yuqing Zhao ,  Han Li ,  Bin Tian ,  Yongbo Wang ,  Liang Qi ,  Gennian Mao

发明人： Chengyuan Liang ,  Wenjing Yang ,  Qianqian Zhao ,  Liang Xin ,  Jingyi Li ,  Dan Yang ,  Ruina Bian ,  Jie Zhang ,  Yuqing Zhao ,  Han Li ,  Bin Tian ,  Yongbo Wang ,  Liang Qi ,  Gennian Mao

IPC分类号： C07D233/60 ,  A61K31/4164 ,  A61P31/04

摘要： A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

公开(公告)号：US11512049B2

公开(公告)日：2022-11-29

申请号：US17239582

申请日：2021-04-24

申请人： Qianqian Zhao ,  Yuqing Zhao ,  Dan Yang ,  Jingyi Li ,  Liang Xin ,  Ruina Bian ,  Jie Zhang ,  Han Li ,  Bin Tian ,  Yongbo Wang ,  Chengyuan Liang ,  Liang Qi ,  Gennian Mao

发明人： Qianqian Zhao ,  Yuqing Zhao ,  Dan Yang ,  Jingyi Li ,  Liang Xin ,  Ruina Bian ,  Jie Zhang ,  Han Li ,  Bin Tian ,  Yongbo Wang ,  Chengyuan Liang ,  Liang Qi ,  Gennian Mao

IPC分类号： C07C323/52 ,  A61P31/04 ,  C07C319/28

摘要： A compound with anti-drug resistant bacteria activity having the formula (I): (I) is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

公开(公告)号：US10941120B1

公开(公告)日：2021-03-09

申请号：US16909862

申请日：2020-06-23

申请人： Han Li ,  Nan Hui ,  Chengyuan Liang ,  Xingke Ju ,  Guaiping Qiao ,  Juan Li ,  Yuanyuan He ,  Bin Tian ,  Yongbo Wang ,  Jingwen Xu ,  Liang Qi ,  Dan Yang ,  Qianqian Zhao ,  Yanjun Li ,  Qiao Zeng ,  Gennian Mao ,  Limei Wang

发明人： Han Li ,  Nan Hui ,  Chengyuan Liang ,  Xingke Ju ,  Guaiping Qiao ,  Juan Li ,  Yuanyuan He ,  Bin Tian ,  Yongbo Wang ,  Jingwen Xu ,  Liang Qi ,  Dan Yang ,  Qianqian Zhao ,  Yanjun Li ,  Qiao Zeng ,  Gennian Mao ,  Limei Wang

IPC分类号： C07D239/545

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US11555016B2

公开(公告)日：2023-01-17

申请号：US17157916

申请日：2021-01-25

申请人： Yongbo Wang ,  Han Li ,  Gennian Mao ,  Bin Tian ,  Dan Yang ,  Chengyuan Liang ,  Xiuding Yang ,  Wenbo Yao ,  Guaiping Qiao ,  Nan Hui ,  Juan Li ,  Liang Xin ,  Jingyi Li ,  Ruina Bian

发明人： Yongbo Wang ,  Han Li ,  Gennian Mao ,  Bin Tian ,  Dan Yang ,  Chengyuan Liang ,  Xiuding Yang ,  Wenbo Yao ,  Guaiping Qiao ,  Nan Hui ,  Juan Li ,  Liang Xin ,  Jingyi Li ,  Ruina Bian

IPC分类号： C07D215/233 ,  A61P31/04

摘要： A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

公开(公告)号：US10947182B1

公开(公告)日：2021-03-16

申请号：US16914326

申请日：2020-06-27

申请人： Han Li ,  Nan Hui ,  Chengyuan Liang ,  Xingke Ju ,  Guaiping Qiao ,  Juan Li ,  Yuanyuan He ,  Bin Tian ,  Yongbo Wang ,  Jingwen Xu ,  Liang Qi ,  Dan Yang ,  Qiangian Zhao ,  Yanjun Li ,  Qiao Zeng ,  Gennian Mao ,  Limei Wang

发明人： Han Li ,  Nan Hui ,  Chengyuan Liang ,  Xingke Ju ,  Guaiping Qiao ,  Juan Li ,  Yuanyuan He ,  Bin Tian ,  Yongbo Wang ,  Jingwen Xu ,  Liang Qi ,  Dan Yang ,  Qiangian Zhao ,  Yanjun Li ,  Qiao Zeng ,  Gennian Mao ,  Limei Wang

IPC分类号： C07C69/94

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US10377702B1

公开(公告)日：2019-08-13

申请号：US16426560

申请日：2019-05-30

申请人： Chengyuan Liang ,  Yuzhi Liu ,  Xingke Ju ,  Yonghong Tang ,  Gennian Mao ,  Qianqian Zhao ,  Bin Tian ,  Jian Zha ,  Chunyang Shi ,  Yongbo Wang ,  Huayin Pu ,  Yanghan Liu

发明人： Chengyuan Liang ,  Yuzhi Liu ,  Xingke Ju ,  Yonghong Tang ,  Gennian Mao ,  Qianqian Zhao ,  Bin Tian ,  Jian Zha ,  Chunyang Shi ,  Yongbo Wang ,  Huayin Pu ,  Yanghan Liu

IPC分类号： C07C269/02 ,  B01J31/02 ,  B01D15/16

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US10995053B1

公开(公告)日：2021-05-04

申请号：US16826045

申请日：2020-03-20

申请人： Han Li ,  Nan Hui ,  Bin Tian ,  Xingke Ju ,  Yuzhi Liu ,  Dan Yang ,  Jingwen Xu ,  Liang Qi ,  Qianqian Zhao ,  Yongbo Wang

发明人： Han Li ,  Nan Hui ,  Bin Tian ,  Xingke Ju ,  Yuzhi Liu ,  Dan Yang ,  Jingwen Xu ,  Liang Qi ,  Qianqian Zhao ,  Yongbo Wang

IPC分类号： C07C67/08 ,  B01J20/291 ,  B01J31/02

摘要： A compound having the formula (I): is disclosed. Methods of preparing the compound of formula (I) are also disclosed. The compound of formula (I) can be prepared by reacting a compound of formula (II) with a compound of formula (III) in an organic solvent with EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide). The compound of formula (I) can also be prepared by reacting the compound of formula (II) with the compound of formula (III) in 1-ethyl-3-methylimidazolium hexafluorophosphate as a solvent with silicomolybdic acid as a catalyst.