公开(公告)号：US20150328271A1

公开(公告)日：2015-11-19

申请号：US14653873

申请日：2012-12-27

Applicant: DAEJEON UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION

Inventor： Chang Gue Son

IPC: A61K36/537 ,  A23L1/30 ,  A61K36/481

CPC classification number: A61K36/481 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/537 ,  A61K2300/00

Abstract: Provided is a composition for preventing or treating oxidative brain injury and brain dysfunction including an extract of Astragali Radix and Salvia Miltiorrhizae Radix as an active ingredient, the composition having a highly outstanding preventive or therapeutic effect in animal models simulating brain-tissue damage and brain dysfunction induced by acute and long-term excessive stress generated in actual clinical practice, which is effectively usable as a therapeutic agent thereof.

Abstract translation: 提供了用于预防或治疗氧化性脑损伤和脑功能障碍的组合物，包括黄芪和丹参的提取物作为活性成分，该组合物在模拟脑组织损伤和脑功能障碍的动物模型中具有非常优异的预防或治疗效果 由实际临床实践中产生的急性和长期过度应激引起的，其可有效用作其治疗剂。

公开(公告)号：US20150335693A1

公开(公告)日：2015-11-26

申请号：US14717474

申请日：2015-05-20

Applicant: Daejeon University Industry-University Cooperation Foundation

Inventor： Chang Gue Son

IPC: A61K36/27

CPC classification number: A61K36/27

Abstract: Provided is a preparation method of an anti-tumor composition having a cancer cell proliferation-suppressing effect containing Cynanchi atrati Radix extracts obtained by solvent-extracting Cynanchi atrati Radix, which is a medicinal herb having the cancer cell proliferation-suppressing effect. The Cynanchi atrati Radix extracts may have a melanoma-specific cancer cell proliferation-suppressing effect, thereby making it possible to provide an anti-tumor composition for preventing and treating malignant melanoma.

Abstract translation: 提供一种具有癌细胞增殖抑制作用的抗肿瘤组合物的制备方法，其含有通过溶剂萃取Cynanchi atrati Radix提取的Cynanchi atrati Radix提取物，Cynanchi atrati Radix是具有癌细胞增殖抑制作用的药草。 Cynanchi atrati Radix提取物可能具有黑素瘤特异性癌细胞增殖抑制作用，从而可以提供用于预防和治疗恶性黑素瘤的抗肿瘤组合物。

公开(公告)号：US10195240B2

公开(公告)日：2019-02-05

申请号：US14653873

申请日：2012-12-27

Applicant: Daejeon University Industry-University Cooperation Foundation

Inventor： Chang Gue Son

IPC: A61K36/481 ,  A61K36/537 ,  A23L33/105

Abstract: Provided is a composition for preventing or treating oxidative brain injury and brain dysfunction including an extract of Astragali Radix and Salvia Miltiorrhizae Radix as an active ingredient, the composition having a highly outstanding preventive or therapeutic effect in animal models simulating brain-tissue damage and brain dysfunction induced by acute and long-term excessive stress generated in actual clinical practice, which is effectively usable as a therapeutic agent thereof.