公开(公告)号：US20220259198A1

公开(公告)日：2022-08-18

申请号：US17552577

申请日：2021-12-16

申请人： Cyteir Therapeutics, Inc.

发明人： Jean-Marc LAPIERRE ,  Casey Cameron MCCOMAS ,  Joseph VACCA

IPC分类号： C07D417/14 ,  C07D417/12 ,  C07D471/04 ,  C07D277/30

摘要： This application is directed to inhibitors of RAD51 represented by the following structural formula, and methods for their use, such as to treat cancer, autoimmune diseases, immune deficiencies, or neurodegenerative diseases.

公开(公告)号：US20200291014A1

公开(公告)日：2020-09-17

申请号：US16816393

申请日：2020-03-12

申请人： Cyteir Therapeutics, Inc.

发明人： Jean-Marc LAPIERRE ,  Casey Cameron MCCOMAS ,  Joseph VACCA

IPC分类号： C07D417/14 ,  C07D277/30 ,  C07D471/04 ,  C07D417/12

摘要： This application is directed to inhibitors of RAD51 represented by the following structural formula, and methods for their use, such as to treat cancer, autoimmune diseases, immune deficiencies, or neurodegenerative diseases.

公开(公告)号：US20240360120A1

公开(公告)日：2024-10-31

申请号：US18427164

申请日：2024-01-30

申请人： Cyteir Therapeutics, Inc.

发明人： Jean-Marc LAPIERRE ,  Casey Cameron MCCOMAS ,  Joseph VACCA

IPC分类号： C07D417/14 ,  C07D277/30 ,  C07D417/12 ,  C07D471/04

CPC分类号： C07D417/14 ,  C07D277/30 ,  C07D417/12 ,  C07D471/04

摘要： This application is directed to inhibitors of RAD51 represented by the following structural formula,




and methods for their use, such as to treat cancer, autoimmune diseases, immune deficiencies, or neurodegenerative diseases.

公开(公告)号：US20210275503A1

公开(公告)日：2021-09-09

申请号：US17191220

申请日：2021-03-03

申请人： Cyteir Therapeutics, Inc.

发明人： Thomas O'SHEA ,  Markus RENSCHLER ,  Todd BOWSER ,  Jean-Marc LAPIERRE ,  Kevin MILLS

IPC分类号： A61K31/426 ,  A61P35/00

摘要： This application is directed to inhibitors of RAD51 represented by the following structural formula, and methods for its use, such as to treat cancer.