公开(公告)号：US20170029407A1

公开(公告)日：2017-02-02

申请号：US15303277

申请日：2016-04-15

申请人： Cocrystal Pharma, Inc. ,  Emory University

发明人： Steven J. Coats ,  Richard Anthony Whitaker ,  Tamara Rosario McBrayer ,  Junxing Shi ,  Franck Amblard ,  Hongwang Zhang ,  Longhu Zhou ,  Raymond F. Schinazi

IPC分类号： C07D401/14 ,  A61K45/06 ,  A61K31/4178

CPC分类号： C07D401/14 ,  A61K31/4178 ,  A61K45/06 ,  C07D403/14

摘要： The present invention is directed to compounds, compositions and methods for treating or preventing hepatitis C virus (HCV) infection in human subjects or other animal hosts. The compounds are as also pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof as pharmaceutical compositions and methods for treatment or prevention of HCV infection.

摘要翻译： 本发明涉及用于治疗或预防人受试者或其他动物宿主中丙型肝炎病毒（HCV）感染的化合物，组合物和方法。 作为用于治疗或预防HCV感染的药物组合物和方法，化合物也是其药学上可接受的盐，前药和其它衍生物。

公开(公告)号：US09181227B2

公开(公告)日：2015-11-10

申请号：US14455197

申请日：2014-08-08

申请人： Cocrystal Pharma, Inc. ,  Emory University

发明人： Steven J. Coats ,  Franck Amblard ,  Hongwang Zhang ,  Longhu Zhou ,  Richard Anthony Whitaker ,  Tamara Rosario McBrayer ,  Raymond F. Schinazi ,  Junxing Shi

IPC分类号： A61K31/4178 ,  C07D407/14 ,  A61K31/4192 ,  C07D403/04 ,  C07D403/14 ,  C07D405/14 ,  C07D413/14 ,  A61K31/444 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/655 ,  A61K45/06 ,  C07D401/14

CPC分类号： C07D403/14 ,  A61K31/4178 ,  A61K31/4192 ,  A61K31/444 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/655 ,  A61K45/06 ,  C07D401/14 ,  C07D403/04 ,  C07D405/14 ,  C07D407/14 ,  C07D413/14

摘要： The present invention is directed to compounds, compositions and methods for treating or preventing hepatitis C virus (HCV) infection in human subjects or other animal hosts. The compounds are as also pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof as pharmaceutical compositions and methods for treatment or prevention of HCV infection.

摘要翻译： 本发明涉及用于治疗或预防人受试者或其他动物宿主中丙型肝炎病毒（HCV）感染的化合物，组合物和方法。 作为用于治疗或预防HCV感染的药物组合物和方法，化合物也是其药学上可接受的盐，前药和其它衍生物。

公开(公告)号：US09926295B2

公开(公告)日：2018-03-27

申请号：US15303277

申请日：2015-04-15

申请人： Cocrystal Pharma, Inc. ,  Emory University

发明人： Steven J. Coats ,  Richard Anthony Whitaker ,  Tamara Rosario McBrayer ,  Junxing Shi ,  Franck Amblard ,  Hongwang Zhang ,  Longhu Zhou ,  Raymond F. Schinazi

IPC分类号： C07D401/14 ,  A61K31/4178 ,  A61K45/06 ,  C07D403/14

CPC分类号： C07D401/14 ,  A61K31/4178 ,  A61K45/06 ,  C07D403/14

摘要： The present invention is directed to compounds, compositions and methods for treating or preventing hepatitis C virus (HCV) infection in human subjects or other animal hosts. The compounds are as also pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof as pharmaceutical compositions and methods for treatment or prevention of HCV infection.

公开(公告)号：US20160068518A1

公开(公告)日：2016-03-10

申请号：US14936878

申请日：2015-11-10

申请人： Cocrystal Pharma, LLC ,  Emory University

发明人： Steven J. Coats ,  Franck Amblard ,  Hongwang Zhang ,  Longhu Zhou ,  Richard Anthony Whitaker ,  Tamara Rosario McBrayer ,  Raymond F. Schinazi ,  Junxing Shi

IPC分类号： C07D403/14 ,  A61K45/06 ,  A61K31/4192 ,  C07D403/04 ,  A61K31/4178

CPC分类号： C07D403/14 ,  A61K31/4178 ,  A61K31/4192 ,  A61K31/444 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/655 ,  A61K45/06 ,  C07D401/14 ,  C07D403/04 ,  C07D405/14 ,  C07D407/14 ,  C07D413/14

摘要： The present invention is directed to compounds, compositions and methods for treating or preventing hepatitis C virus (HCV) infection in human subjects or other animal hosts. The compounds are as also pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof as pharmaceutical compositions and methods for treatment or prevention of HCV infection.

公开(公告)号：US09932326B2

公开(公告)日：2018-04-03

申请号：US14936878

申请日：2015-11-10

申请人： Cocrystal Pharma, LLC ,  Emory University

发明人： Steven J. Coats ,  Franck Amblard ,  Hongwang Zhang ,  Longhu Zhou ,  Richard Anthony Whitaker ,  Tamara Rosario McBrayer ,  Raymond F. Schinazi ,  Junxing Shi

IPC分类号： A61K31/4178 ,  C07D403/14 ,  C07D403/04 ,  C07D405/14 ,  C07D413/14 ,  A61K31/4192 ,  A61K31/444 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/655 ,  C07D401/14 ,  C07D407/14 ,  A61K45/06

CPC分类号： C07D403/14 ,  A61K31/4178 ,  A61K31/4192 ,  A61K31/444 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/655 ,  A61K45/06 ,  C07D401/14 ,  C07D403/04 ,  C07D405/14 ,  C07D407/14 ,  C07D413/14

摘要： The present invention is directed to compounds, compositions and methods for treating or preventing hepatitis C virus (HCV) infection in human subjects or other animal hosts. The compounds are as also pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof as pharmaceutical compositions and methods for treatment or prevention of HCV infection.

公开(公告)号：US20140350016A1

公开(公告)日：2014-11-27

申请号：US14455197

申请日：2014-08-08

申请人： RFS Pharma, LLC ,  Emory University

发明人： Steven J. Coats ,  Franck Amblard ,  Hongwang Zhang ,  Longhu Zhou ,  Richard Anthony Whitaker ,  Tamara Rosario McBrayer ,  Raymond F. Schinazi ,  Junxing Shi

IPC分类号： C07D407/14 ,  A61K31/4178 ,  C07D403/14 ,  A61K45/06 ,  A61K31/5377 ,  C07D401/14 ,  A61K31/444 ,  A61K31/506 ,  C07D403/04 ,  A61K31/4192

CPC分类号： C07D403/14 ,  A61K31/4178 ,  A61K31/4192 ,  A61K31/444 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/655 ,  A61K45/06 ,  C07D401/14 ,  C07D403/04 ,  C07D405/14 ,  C07D407/14 ,  C07D413/14

摘要： The present invention is directed to compounds, compositions and methods for treating or preventing hepatitis C virus (HCV) infection in human subjects or other animal hosts. The compounds are as also pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof as pharmaceutical compositions and methods for treatment or prevention of HCV infection.

摘要翻译： 本发明涉及用于治疗或预防人受试者或其他动物宿主中丙型肝炎病毒（HCV）感染的化合物，组合物和方法。 作为用于治疗或预防HCV感染的药物组合物和方法，化合物也是其药学上可接受的盐，前药和其它衍生物。