公开(公告)号：US20240384345A1

公开(公告)日：2024-11-21

申请号：US18533936

申请日：2023-12-08

Applicant: China Medical University

Inventor： Chin-Chi Kuo ,  Hung-Lin Chen ,  Hsiu-Yin Chiang

IPC: C12Q1/6883 ,  G16B5/00 ,  G16B20/20 ,  G16B30/10 ,  G16B40/20 ,  G16H50/30 ,  G16H50/70

Abstract: A method for assessing risk of chronic kidney disease includes following steps. A reference database is provided. A nucleic acid sample and a biological dataset of a subject are provided. A genetic testing step is performed. A risk score calculating step is performed. A model establishing step is performed, wherein a plurality of reference polygenic risk score data, a plurality of reference clinical data and a plurality of reference genetic marker data of the reference database are trained to achieve a convergence by a machine learning algorithm so as to obtain an analysis model. A data analysis step is performed, wherein a polygenic risk score, a clinical data and a genetic marker data of a subject are analyzed by the analysis model so as to obtain a risk analysis result.

公开(公告)号：US20240145094A1

公开(公告)日：2024-05-02

申请号：US18499386

申请日：2023-11-01

Applicant: China Medical University

Inventor： Chin-Chi Kuo ,  Sheng-Ya Lu ,  Hsiu-Yin Chiang ,  Yu-Ting Lin

IPC: G16H50/20 ,  A61B5/00 ,  A61B5/346 ,  G16H50/50

CPC classification number: G16H50/20 ,  A61B5/346 ,  A61B5/7267 ,  G16H50/50

Abstract: A method for assessing occurrence of heart failure includes the following steps. A heart failure assessment program established is provided. A target ECG signal data of the subject is provided, wherein the target ECG signal data includes a plurality of target heartbeat waveform data and a plurality of target heart rate data. A data pre-processing step is performed, wherein the target ECG signal data is pre-processed by the data processing module so as to obtain a processed target ECG signal data. An analyzing step is performed, wherein the processed target ECG signal data is analyzed by the heart failure assessment program so as to obtain a heart failure occurrence assessing result, and the heart failure occurrence assessing result presents a heart failure occurring condition and the severity of the heart failure of the subject.

公开(公告)号：US20230420135A1

公开(公告)日：2023-12-28

申请号：US18337225

申请日：2023-06-19

Applicant: China Medical University

Inventor： Chin-Chi Kuo ,  Che-Chen Lin ,  Hsiu-Yin Chiang ,  Min-Yen Wu

IPC: G16H50/20 ,  A61B5/00 ,  G16H10/60

CPC classification number: G16H50/20 ,  G16H10/60 ,  A61B5/4866

Abstract: A method for assessing fasting status includes the following steps. A fasting blood glucose database is provided, wherein the fasting blood glucose database includes a plurality of fasting blood glucose data and a plurality of non-fasting blood glucose data. A model establishing step is performed, wherein the plurality of fasting blood glucose data and the plurality of non-fasting blood glucose data are trained to achieve a convergence by a machine-learning model so as to obtain a fasting-status assessing classifier. An ontological data of a subject is provided, wherein the ontological data includes a blood glucose concentration data. An assessing step is performed, wherein the ontological data is analyzed by the fasting-status assessing classifier to obtain an assessing result of fasting status of the subject.

公开(公告)号：US20250054627A1

公开(公告)日：2025-02-13

申请号：US18799046

申请日：2024-08-09

Applicant: China Medical University

Inventor： Chin-Chi Kuo ,  Hsiu-Yin Chiang ,  Hung-Chieh Yeh ,  Sheng-Ya Lu ,  Yi-Ching Chang

IPC: G16H50/20 ,  G16H10/60

Abstract: A method for assessing acute kidney injury of inpatient includes the following steps. An electronic medical record data of an inpatient is captured by a processor, and the electronic medical record data includes a baseline basic serum creatinine concentration data. A target serum creatinine concentration data and a minimum post-admission serum creatinine concentration data of the inpatient are captured by the processor. A dynamic-increasing value of serum creatinine concentration is calculated to obtain by the processor based on the target serum creatinine concentration data, the baseline basic serum creatinine concentration data and the minimum post-admission serum creatinine concentration data. The dynamic-increasing value of serum creatinine concentration is analyzed by the processor to assess whether the inpatient is an inpatient suffering the acute kidney injury or not.