公开(公告)号：US20240360417A1

公开(公告)日：2024-10-31

申请号：US18631774

申请日：2024-04-10

Applicant: Cell&Brain Co., Ltd

Inventor： Hae Young SUH ,  Sung Soo KIM ,  Da Young CHANG ,  Jin Hwa JUNG ,  Young Don LEE ,  Woo Sup HWANG ,  Jin Sung PARK ,  Su Jung LEE

IPC: C12N5/0775 ,  A61K31/4188 ,  A61K31/4745 ,  A61K31/506 ,  A61K31/513 ,  A61K31/675 ,  A61K31/704 ,  A61K33/243 ,  A61K33/244 ,  A61K35/12 ,  A61K35/28 ,  A61K45/06

CPC classification number: C12N5/0665 ,  A61K31/4188 ,  A61K31/4745 ,  A61K31/506 ,  A61K31/513 ,  A61K31/675 ,  A61K31/704 ,  A61K33/243 ,  A61K33/244 ,  A61K35/12 ,  A61K35/28 ,  A61K45/06 ,  C12N5/0663 ,  C12N2501/73 ,  C12N2510/00 ,  C12N2523/00

Abstract: The present disclosure relates to a method for preparing cells for cancer treatment and a kit for cancer treatment comprising cells prepared by the method. The preparation method of the present disclosure can provide F cells, which, in spite of having no difference in the proliferative capacity compared with mesenchymal stem cells expressing cytosine deaminase that are harvested and used immediately after the culture, exhibit a very excellent tumor suppressive effect through the treatment together with 5-FC and induce a remarkable synergistic effect exceeding an effect from combinative treatment with an existing anticancer drug in cases of a combinative treatment with another anticancer drug. Therefore, the present disclosure can be utilized for a kit for cancer treatment comprising such F cells, and thus can be favorably used to maximize the effect of existing cancer treatments.

公开(公告)号：US20240331802A1

公开(公告)日：2024-10-03

申请号：US18251138

申请日：2021-08-27

Applicant: CELL&BRAIN CO., LTD.

Inventor： Hae Young SUH ,  Au Jin KIM ,  Da Young CHANG ,  Sung Soo KIM ,  Sang Ho KIM

IPC: G16B30/00

CPC classification number: G16B30/00

Abstract: A gene insertion location analysis system for a stem cell therapeutic agent having a specific gene inserted therein comprises: a basic information management unit for managing information essential for operating a gene insertion location analysis system for a stem cell therapeutic agent having a specific gene inserted therein; a gene insertion location analysis unit for managing information for the gene insertion location analysis system; and a DB management unit for managing a DB generated or referred by the basic information management unit and gene insertion location analysis unit.