公开(公告)号：US20230234920A1

公开(公告)日：2023-07-27

申请号：US18007960

申请日：2021-06-04

申请人： COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH

发明人： Gangarajula SUDHAKAR ,  Nagam SATISH ,  Tella Ramesh BABU ,  Kumaravelu JAGAVELU ,  Himalaya SINGH ,  Mohammad Imran SIDDIQI ,  Muhammad WAHAJUDDIN ,  Sandeep Kumar SINGH ,  Mamunur RASHID ,  Anil Kumar Karunakaran SASIKALA

IPC分类号： C07D203/04 ,  C07D405/06 ,  C07D403/06 ,  C07F9/564 ,  C07D405/12 ,  C07D403/04 ,  A61P9/00

CPC分类号： C07D203/04 ,  C07D405/06 ,  C07D403/06 ,  C07F9/564 ,  C07D405/12 ,  C07D403/04 ,  A61P9/00

摘要： The present invention relates to azirine containing compounds useful as anti-angiogenesis agents and preparation thereof. Particularly the present invention relates to azirine containing compounds of formula I, Formula I wherein R1, R2 and R3 are same as defined in the description. The compounds of the present invention are with asymmetric centers this, they are mixture of enantiomers and mixture of diastereomers in some cases. The present invention includes the individual enantiomers and diastereomeric forms of the compound formula I besides the mixtures thereof.