公开(公告)号：US11634721B2

公开(公告)日：2023-04-25

申请号：US15833168

申请日：2017-12-06

Applicant: CORTEVA AGRISCIENCE LLC

Inventor： David R. Corbin ,  Wei Chen ,  Stephen Novak ,  Ryan M. Lee ,  Sandeep Kumar ,  Andrew Asberry ,  Andrew F. Worden

IPC: C12N15/82 ,  C12N9/22 ,  C12N15/90

Abstract: Disclosed herein are methods and compositions for the repair of site specific nuclease binding sites by targeted integration and/or targeted excision of one or more sequences into a cell.

公开(公告)号：US11519000B2

公开(公告)日：2022-12-06

申请号：US16994734

申请日：2020-08-17

Applicant: CORTEVA AGRISCIENCE LLC

Inventor： Sandeep Kumar ,  Ryan M. Lee ,  Stephen Novak ,  Andrew F. Worden

IPC: C12N15/82

Abstract: The current disclosure relates to methods and compositions for improving plant varieties through plant breeding and plant genetics. For instance, the disclosure concerns increasing the recombination frequency of a heterozygous trait genetically linked to a second trait within plants. Further, the disclosure concerns breaking the genetic linkage between a first allele and a second allele.