公开(公告)号：US20220380304A1

公开(公告)日：2022-12-01

申请号：US17622322

申请日：2020-07-02

申请人： CKD BIO CORPORATION

发明人： Hee Un KIM ,  In Kyu KIM ,  Myeong Seok LEE ,  Heung Mo KANG ,  Sae Jin KIM ,  In Suk CHOI

IPC分类号： C07C277/08

摘要： The present invention relates to a method for producing peramivir trihydrate, which is an inhibitor of neuraminidase infection, as an anti-influenza agent. According to the production method of the present invention, peramivir trihydrate can be produced with high yield and stability through a process suitable for producing excellent pharmaceuticals and quality control standards (GMP) without using highly-toxic methanol and activated carbon.