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公开(公告)号:US20150159221A1
公开(公告)日:2015-06-11
申请号:US14407046
申请日:2013-06-14
发明人: Robert C. Seeger , Shahab Asgharzadeh , Weiyao Liu , Richard Sposto , Lingyun Ji
CPC分类号: C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/16 , G01N2333/4703 , G01N2333/4706 , G01N2333/49 , G01N2333/52 , G01N2333/521 , G01N2333/53 , G01N2333/5406 , G01N2333/5412 , G01N2333/5418 , G01N2333/5421 , G01N2333/5428 , G01N2333/5437 , G01N2333/5443 , G01N2333/57 , G01N2333/70503 , G01N2333/70514 , G01N2333/70517 , G01N2333/70521 , G01N2333/70532 , G01N2333/70535 , G01N2333/70539 , G01N2333/70567 , G01N2333/70578 , G01N2333/70596 , G01N2333/71 , G01N2333/7153 , G01N2333/7155 , G01N2333/7158 , G01N2333/90206 , G01N2333/90245 , G01N2333/912 , G01N2333/916 , G01N2333/96436 , G01N2333/988 , G01N2333/99 , G16B25/00 , G16H50/30
摘要: The present invention provides for molecular analysis of gene expression of tumors at diagnosis as well as molecular analysis of tumor and normal cell gene expression in bone marrow and blood at diagnosis and during and after completion of treatment. These molecular analyses of gene expression provide an assessment of risk of recurrence and response to therapy of tumors, and in particular, neuroblastoma.
摘要翻译: 本发明提供诊断时以及在诊断期间和治疗完成后的骨髓和血液中的肿瘤和正常细胞基因表达的诊断中的基因表达的分子分析。 这些基因表达的分子分析提供了对肿瘤,特别是神经母细胞瘤的复发和反应风险的评估。