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公开(公告)号：US20230165867A1
公开(公告)日：2023-06-01
申请号：US18046879
申请日：2022-10-14
发明人： Yonggang WEI , Xuezhen XU , Hongzhu CHU , Lvxue HE , Feiquan LEI , Jie YAN , Yang HE , Meiwei WANG , Guizhuan SU , Bing LIU , Yi SUN
IPC分类号： A61K31/522 , C07D473/32 , C07D519/00 , A61K31/5377
CPC分类号： A61K31/522 , A61K31/5377 , C07D473/32 , C07D519/00 , C07B2200/05
摘要： The present application relates to imidazolidinone derivatives and medical use thereof, and in particular relates to pyrimidine derivatives represented by general formula (I), or stereoisomers, solvates, metabolites, prodrugs, pharmaceutically acceptable salts or co-crystals thereof, a pharmaceutical composition comprising the same, and use of the compound or pharmaceutical composition according to the present application in the manufacture of a medicament for treatment of cancer.
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公开(公告)号：US20230059087A1
公开(公告)日：2023-02-23
申请号：US17772995
申请日：2021-01-07
发明人： Xibing ZHOU , Jing ZHANG , Xuezhen XU , Yonggang WEI , Hongzhu CHU , Fuqiang ZHAO , Guizhuan SU , Meiwei WANG , Yi SUN
IPC分类号： A61K31/05 , C07C39/19 , C07C69/94 , C07C43/215 , C07C39/08 , C07C65/10 , C07C43/23 , C07C49/825 , C07C37/16 , A61K31/365 , A61K31/235 , A61K31/09
摘要： Cannabidiol derivatives and medical use thereof, in particular to the compounds represented by general formula (I), or stereoisomers, solvates, metabolites, prodrugs, pharmaceutically acceptable salts or cocrystals thereof, wherein the definitions of substituents in general formula (I) are the same as those in the description
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3.发明申请公开(公告)号：US20170319542A1
公开(公告)日：2017-11-09
申请号：US15523239
申请日：2015-10-30
发明人： Yi SUN
IPC分类号： A61K31/365 , A61K31/444 , A61K31/423 , A61K31/4418 , A61K31/5377 , A61K31/4545
CPC分类号： A61K31/365 , A61K9/00 , A61K31/423 , A61K31/437 , A61K31/44 , A61K31/4418 , A61K31/4425 , A61K31/444 , A61K31/4545 , A61K31/5377 , A61K45/06 , A61P7/02 , A61K2300/00
摘要： A pharmaceutical composition containing ginkgolide B and an Xa factor inhibitor xaban, a preparation method and use of the pharmaceutical composition, wherein the xaban is selected from Rivaroxaban, Apixaban, Edoxaban, Razaxaban and Otamixaban.
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公开(公告)号：US20230227482A1
公开(公告)日：2023-07-20
申请号：US17772993
申请日：2021-01-07
发明人： Jing ZHANG , Xuezhen XU , Yonggang WEI , Hongzhu CHU , Fuqiang ZHAO , Guizhuan SU , Meiwei WANG , Yi SUN
IPC分类号： C07F9/655
CPC分类号： C07F9/65522 , C07B2200/05
摘要： Tetrahydrocannabinol derivatives and medical use thereof, in particular to the compounds represented by general formula (I), or stereoisomers, solvates, metabolites, pharmaceutically acceptable salts or cocrystals thereof, wherein the definitions of substituents in general formula (I) are the same as those in the description
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5.发明申请公开(公告)号：US20190142794A1
公开(公告)日：2019-05-16
申请号：US16244593
申请日：2019-01-10
发明人： Yi SUN
IPC分类号： A61K31/365 , A61K45/06 , A61K31/4365 , A61K31/519
摘要： A pharmaceutical composition containing ginkgolide B and an ADP receptor antagonist, a preparation method thereof and use thereof in preparation of antiplatelet drugs, wherein the ADP receptor antagonist is clopidogrel, prasugrel, ticagrelor and/or ticlopidine.
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6.发明申请公开(公告)号：US20170312248A1
公开(公告)日：2017-11-02
申请号：US15522681
申请日：2015-10-28
发明人： Yi SUN
IPC分类号： A61K31/365 , A61K31/519 , A61K31/4365
CPC分类号： A61K31/365 , A61K31/4365 , A61K31/519 , A61K45/06 , A61K2300/00
摘要： A pharmaceutical composition containing ginkgolide B and an ADP receptor antagonist, a preparation method thereof and use thereof in preparation of antiplatelet drugs, wherein the ADP receptor antagonist is clopidogrel, prasugrel, ticagrelor and/or ticlopidine.
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公开(公告)号：US20170273993A1
公开(公告)日：2017-09-28
申请号：US15513941
申请日：2015-09-25
发明人： Yi SUN
IPC分类号： A61K31/616 , A61K31/365
CPC分类号： A61K31/616 , A61K31/365 , A61K2300/00
摘要： Provided is a pharmaceutical composition containing ginkgolide B and the blood platelet prostaglandin cyclooxygenase inhibitor aspirin, a method for preparation of the pharmaceutical composition and a use thereof. When used together, ginkgolide B and aspirin have a synergistic effect in resisting platelet aggregation.
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公开(公告)号：US20240158406A1
公开(公告)日：2024-05-16
申请号：US18515434
申请日：2023-11-21
发明人： Yonggang WEI , Yuqin ZHU , Hongzhu CHU , Fei YE , Wutong DENG , Wei LIU , Yi SUN
IPC分类号： C07D487/04 , A61P35/00 , C07D471/04 , C07D519/00
CPC分类号： C07D487/04 , A61P35/00 , C07D471/04 , C07D519/00
摘要： The present application relates to a piperazine-based compound and a composition thereof, and the use thereof in the manufacture of an anti-tumor medicament.
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公开(公告)号：US20240018079A1
公开(公告)日：2024-01-18
申请号：US18253877
申请日：2021-11-25
发明人： Yi SUN , Xuezhen XU , Jing ZHANG , Yonggang WEI
CPC分类号： C07C37/685 , C07C39/23 , C07C37/88
摘要： Disclosed is a method for purifying cannabinoid compounds that enables cannabinoid compounds to be obtained more economically and with a better purification effect.
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公开(公告)号：US20230002425A1
公开(公告)日：2023-01-05
申请号：US17772126
申请日：2021-01-07
发明人： Xuezhen XU , Jing ZHANG , Yonggang WEI , Hongzhu CHU , Fuqiang ZHAO , Guizhuan SU , Meiwei WANG , Yi SUN
IPC分类号： C07F9/36
摘要： Cannabidiol derivatives and medical use thereof, in particular to compounds represented by general formula (I), or stereoisomers, solvates, metabolites, pharmaceutically acceptable salts or cocrystals thereof, wherein the definitions of the substituents in general formula (I) are the same as those in the description.
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