公开(公告)号：US20240190875A1

公开(公告)日：2024-06-13

申请号：US18547364

申请日：2022-04-24

申请人： CHANGCHUN GENESCIENCE PHARMACEUTICAL CO., LTD.

发明人： Yunlong SONG ,  Guangyuan SHEN ,  Peng LIU ,  Lei JIN ,  Guocheng WANG ,  Daizong LIN ,  Guosheng TENG ,  Hongbo YAN

IPC分类号： C07D471/10 ,  A61K31/438

CPC分类号： C07D471/10 ,  A61K31/438

摘要： A compound of Formula I, or a racemate, a racemate, a stereoisomer, a tautomer, an isotopically labeled compound, an N-oxide, a solvate, a polymorph, a metabolite, an ester, a prodrug or a pharmaceutically acceptable salt thereof are provided. Also provided is a pharmaceutical composition containing the compound of Formula I and derivatives, a preparation method therefor, and use thereof as a GHSR agonist in the preparation of drugs for diagnosing, preventing and/or treating growth hormone dependent disease. The structure of Formula I is shown below: