公开(公告)号：US10899713B2

公开(公告)日：2021-01-26

申请号：US16421671

申请日：2019-05-24

申请人： CADILA HEALTHCARE LIMITED

发明人： Ranjit C. Desai ,  Rajiv Sharma ,  Vrajesh Pandya ,  Kalpesh Shah ,  Sunil Patel ,  Rakesh Chauhan ,  Ranjeet Nair ,  Vivek Joshi ,  Manoj Patel ,  Mrigendra Shukla

IPC分类号： C07D215/58 ,  C07D215/56

摘要： The present invention relates to an improved process for the preparation of quinolone based compounds of general formula (I) using intermediate compound of general formula (XII). Invention also provides an improved process for the preparation of compound of formula (I-a) using intermediate compound of formula (XII-a) and some novel impurities generated during process. Compounds prepared using this process can be used to treat anemia.

公开(公告)号：US09242926B2

公开(公告)日：2016-01-26

申请号：US14302749

申请日：2014-06-12

申请人： CADILA HEALTHCARE LIMITED

发明人： Bipin Pandey ,  Kalpesh Shah

IPC分类号： C07C271/02 ,  C07C231/14 ,  C07C231/24 ,  C07C271/22 ,  C07C237/22 ,  C07C231/12

CPC分类号： C07C231/12 ,  C07C231/24 ,  C07C237/22 ,  C07C271/22

摘要： The invention relates to improved processes for the preparation of lacosamide. The invention also relates to a novel intermediate useful in the preparation of lacosamide. The invention also relates to process for the purification of lacosamide.

摘要翻译： 本发明涉及用于制备lacosamide的改进方法。 本发明还涉及一种可用于制备lacosamide的新型中间体。 本发明还涉及lacosamide的纯化方法。