公开(公告)号：US20200291015A1

公开(公告)日：2020-09-17

申请号：US16083951

申请日：2017-03-10

Applicant: Bristol-Myers Squibb Company

Inventor： Joanne M. Smallheer ,  Carol Hui HU ,  Meriah Neissel Valente ,  Scott A. Shaw ,  Benjamin P. Vokits ,  Oz Scott Halpern

IPC: C07D471/04

Abstract: The present invention provides compounds of Formula (I). wherein A and Z are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and may be useful for the treatment and/or prophylaxis of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.