公开(公告)号：US20150258539A1

公开(公告)日：2015-09-17

申请号：US14657701

申请日：2015-03-13

Applicant: Bio-Rad Laboratories, Inc. ,  Rensselaer Polytechnic Institute

Inventor： Steven Cramer ,  James Woo ,  Hong Chen ,  Jiali Liao ,  Russell Frost

IPC: B01J39/20 ,  C07K1/16

Abstract: Mixed mode ligands, as well their use for purifying proteins, are provided.

Abstract translation: 提供了混合模式配体，以及它们用于纯化蛋白质的用途。

公开(公告)号：US10583429B2

公开(公告)日：2020-03-10

申请号：US14657701

申请日：2015-03-13

Applicant: Bio-Rad Laboratories, Inc. ,  Rensselaer Polytechnic Institute

Inventor： Steven Cramer ,  James Woo ,  Hong Chen ,  Jiali Liao ,  Russell Frost

IPC: B01J39/26 ,  B01J39/20 ,  C07K1/16 ,  B01J20/286 ,  B01J20/32 ,  B01J20/28

Abstract: The present disclosure is directed to mixed mode chromatography media comprising a ligand directly attached to a solid support. In some aspects, the ligand has a chemical formula of The mixed mode chromatography media is useful for binding and purifying proteins from a solution.