公开(公告)号：US11193176B2

公开(公告)日：2021-12-07

申请号：US14587365

申请日：2014-12-31

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Michael Samuels ,  Darren R. Link ,  Sirshendu Roopom Banerjee

IPC: C12Q1/70

Abstract: The invention includes methods for determining the presence of a latent viral population by analyzing an RNA population from the virus with digital techniques, such as digital PCR or by sequencing cDNA produced from the RNA. The invention additional includes methods for determining the presence of latent viral populations by detecting and/or quantifying enzymes that are uniquely associated with the virus, e.g., reverse transcriptases.

公开(公告)号：US20220033919A1

公开(公告)日：2022-02-03

申请号：US17502251

申请日：2021-10-15

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Michael L. Samuels ,  Darren R. Link ,  Sirshendu Roopom Banerjee

IPC: C12Q1/70

Abstract: The invention includes methods for determining the presence of a latent viral population by analyzing an RNA population from the virus with digital techniques, such as digital PCR or by sequencing cDNA produced from the RNA. The invention additional includes methods for determining the presence of latent viral populations by detecting and/or quantifying enzymes that are uniquely associated with the virus, e.g., reverse transcriptases.