专利检索 ap:("Beth Israel Deaconess Medical Center, Inc.") AND inv:"Menzo J. E. HAVENGA" 第 1 页

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发明公开
RECOMBINANT ADENOVIRUSES AND USES THEREOF 审中-公开

公开(公告)号：US20240287142A1

公开(公告)日：2024-08-29

申请号：US18455151

申请日：2023-08-24

申请人： Beth Israel Deaconess Medical Center, Inc.

发明人： Dan H. BAROUCH , Peter ABBINK , Mark Justin IAMPIETRO , Menzo J. E. HAVENGA

IPC分类号： C07K14/075 , A61K31/7088 , A61K35/761 , A61K39/235 , C07K14/54 , C12N15/861

CPC分类号： C07K14/075 , A61K31/7088 , A61K35/761 , A61K39/235 , C07K14/5425 , C12N15/861

摘要： Featured are recombinant adenoviruses and vectors thereof. In particular, the adenoviruses are simian (rhesus) adenoviruses having a low seroprevalence and high immunogenicity (when expressing, e.g., an antigenic polypeptide) relative to other adenoviruses and vectors thereof. Also featured are methods for producing the adenoviruses and methods of treatment of diseases by administering the adenoviral vector(s) to a subject (e.g., a human).