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1.
公开(公告)号:US20240066216A1
公开(公告)日:2024-02-29
申请号:US18259649
申请日:2021-12-28
Applicant: Becton, Dickinson and Company
Inventor: Alessandro PIZZOCHERO , Mark WOOD , Nicholas ANDERSON
IPC: A61M5/145
CPC classification number: A61M5/1452
Abstract: A fluid delivery device has a syringe barrel with reservoir chamber for fluid, a plunger that translates along a longitudinal axis to expel fluid, and a pusher dimensioned to translate within the barrel and coupled to a drive mechanism to controllably contact and move the plunger. The pusher contacts the plunger at its mechanical center to reduce tilt in the plunger. Contact faces of the pusher and plunger cooperate as a ball joint to minimize non-axial forces on the plunger face. The pusher can have a protrusion of various lengths extending toward and being at least partially received in a recess of various depths in the plunger. The pusher is rigidly connected to a drive mechanism for anti-rotation. The pusher can have scalloped edges for air venting, and apertures for cooperating with protrusions on the drive mechanism to prevent bottoming out the plunger when filling.
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公开(公告)号:US20230067085A1
公开(公告)日:2023-03-02
申请号:US17795811
申请日:2021-01-20
Applicant: Becton, Dickinson and Company
Inventor: Alessandro PIZZOCHERO , Mark WOOD , Russell COLE
IPC: A61M5/142
Abstract: A pump subsystem for fluid delivery (e.g., in a wearable patch pump) is provided wherein pumping action is generated by linear piston movement that pulls a plug, which is interconnected to the piston between two mechanical extremes or end stops in a telescopic or variable volume fluid chamber. Such interconnection enables piston and plug to move a certain distance with respect to each other that corresponds to a predefined swept volume of the pump subsystem. Telescoping-like effect of relative piston and plug movement provides for intake and discharge of fluid with respect to the fluid chamber. Movement of plug within piston can be enabled by the friction of seals placed on the plug, which serve to provide resistance to piston motion and therefore force translation motion of the plug to lag relative to the piston translation motion during portions of the pump cycle.
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公开(公告)号:US20220054740A1
公开(公告)日:2022-02-24
申请号:US17401876
申请日:2021-08-13
Applicant: Becton, Dickinson and Company
Inventor: Mark WOOD , Dana COTE , Alessandro PIZZOCHERO
Abstract: A fluid delivery device has a syringe barrel-type reservoir with plunger and plunger driver assembly comprising nested, telescopic screws comprising an innermost screw keyed to a first side of the plunger or intermediate pusher to prevent rotation. In a fully retracted position, the nested screws do not extend into the reservoir. The nested screws all have right handed threads and employ the same pitch in their respective inner thread and outer thread designs. The outermost screw is connected to a motor for controllable rotation. The decreasing torque ratios from the outermost to innermost screw member and anti-rotation feature allows the innermost screw to advance the plunger into the reservoir before the adjacent concentric screw member commences rotating and advancing within its corresponding screw, and so on, to translate the plunger and expel fluid in a fluid chamber defined on the other, second side of the plunger.
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4.
公开(公告)号:US20240299650A1
公开(公告)日:2024-09-12
申请号:US18661920
申请日:2024-05-13
Applicant: Becton, Dickinson and Company
Inventor: Alessandro PIZZOCHERO , Mark WOOD , Muzaffer Yalgin OZSECEN , Timothy BLUM , Eric HASSENPFLUG , Cory BAKER , Jeffrey HELD
CPC classification number: A61M5/1452 , A61M5/14236 , A61M5/14248
Abstract: A fluid delivery device has a syringe barrel-type reservoir with plunger, and plunger driver assembly comprising double-acting, telescoping lead screws that is located behind and outside of the barrel. Simultaneously and counter-rotating sleeve screw and center screw telescope out of a nested configuration of the plunger driver assembly and into the reservoir at a rate of double their individual and equal pitch and lead parameters when the sleeve screw is rotated. A threaded nut and gear anchor disposed on an end of the barrel receive the sleeve screw and the threaded nut causes the sleeve screw to translate and rotate in response to motor operation. A distal end of the center screw can be keyed to a plunger pusher for anti-rotation constraint when the motor is imparting rotation on the threaded nut and sleeve screw.
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公开(公告)号:US20230381407A1
公开(公告)日:2023-11-30
申请号:US18030845
申请日:2021-10-05
Applicant: Becton, Dickinson and Company
Inventor: Bo Yang YU , Alessandro PIZZOCHERO , J. Richard GYORY , Mark WOOD
CPC classification number: A61M5/14248 , A61M5/1452 , A61M2202/0007 , A61M2005/14533
Abstract: A delivery device for delivering medicament, such as insulin, to a patient includes a housing and a base enclosing an inner cavity. Enclosed within the housing is a reservoir for containing a medicament, a delivery mechanism for delivering the medicament to the patient, and a pump in fluid communication with the reservoir and delivery mechanism. The base has an integrally formed fluid channel covered by a flexible membrane in fluid communication with the reservoir and the delivery mechanism. A peristaltic pump mechanism includes a cam assembly having a plurality of cams and cam follower assembly with a plurality of protrusions to sequentially engaging the flexible membrane to advance the fluid through fluid channel.
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公开(公告)号:US20230064224A1
公开(公告)日:2023-03-02
申请号:US17795863
申请日:2021-01-20
Applicant: Becton, Dickinson and Company
Inventor: Alessandro PIZZOCHERO , Mark WOOD , Shehryar SIDDIQUI , Elizabeth GURIN , Keith KNAPP
Abstract: Pump subsystem for fluid delivery (e.g., in a wearable patch pump) comprises a fluid chamber with pumping motion and a valve shaft assembly with valving motion, both being driven by the same drive mechanism. Fluid chamber has variable volume chamber provided by a piston driven by the drive mechanism and translated relative to a plug in the pump housing. Piston extends the fluid chamber during an intake stroke and retracts the fluid chamber during a discharge stroke. Valve assembly has at least one valve shaft controllably translated by the drive mechanism to selectively align a first throughway with an opening in the pump chamber and a fluid intake port for an intake stroke to draw fluid into the fluid chamber, and align a second throughway with the opening in the pump hamber and a fluid discharge port for an discharge stroke to discharge fluid from the fluid chamber.
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公开(公告)号:US20240390577A1
公开(公告)日:2024-11-28
申请号:US18694137
申请日:2022-09-23
Applicant: Becton, Dickinson and Company
Inventor: Alessandro PIZZOCHERO , Mark WOOD
Abstract: Drug delivery device, drug delivery system, and system components are provided including configuration of a container, reservoir or barrel for medium or fluid and a pump mechanism or driving components for advancing a plunger to dispense the medium or fluid from the reservoir or barrel, and/or for filling the reservoir or barrel with the medium or fluid, where the pumping mechanism or driving components are disposed such that individual and/or overall dimensions of the pump mechanism or the driving components can be reduced compared to conventional designs. A provided system can include a syringe-style drug container, reservoir, or barrel containing a medium or fluid which can be dispensed by a pumping mechanism configured to advance a plunger/stopper disposed inside the barrel via cable, or a ribbon, connected to the plunger/stopper.
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公开(公告)号:US20240285865A1
公开(公告)日:2024-08-29
申请号:US18292532
申请日:2022-07-29
Applicant: Becton, Dickinson and Company
CPC classification number: A61M5/31513 , A61M5/14248 , A61M2005/14506
Abstract: A fluid delivery device has a syringe barrel-type reservoir with plunger and plunger driver assembly comprising a spiral zipper-driven pump mechanism. A flexible band in the spiral zipper-driven pump mechanism is transformed from a collapsed, nested configuration to an extended configuration by controllably unfurling and recoiling the band into a spiral column of interlocking revolutions of the band. The column has sufficient stiffness to impart translational motion to a plunger along a longitudinal reservoir axis that is precisely controllable by rotation of gears by a motor. The collapsed, non-extended configuration of the spiral zipper-driven pump mechanism reduces reservoir and fluid delivery device length.
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公开(公告)号:US20240269385A1
公开(公告)日:2024-08-15
申请号:US18565890
申请日:2022-06-07
Applicant: Becton, Dickinson and Company
Inventor: Dana COTE , J. Richard GYORY , Mark WOOD , Nicholas ANDERSON
CPC classification number: A61M5/1782 , A61M2005/14252 , A61M2209/045
Abstract: A fluid delivery device (110) comprising an integrated vial connector system (180) disposed in a fluid path (124) between a reservoir (122) and an insertion mechanism (116). Additionally, a fluid delivery device (210) and an external fill device (294) wherein when the external fill device (294) engages the fluid delivery device (210), a main drive gear (234) is disengaged and a leadscrew (236) is engaged for filling the fluid delivery device (210) with the medicament. Also, a vial adapter (280) comprising an elastomer (282) that engages an outer diameter of a cannula (217) in an insertion mechanism (216) to provide a sealing surface, wherein the vial adapter (280) engages the fluid delivery device (210) and the vial (202) to fill the fluid delivery device (210) with medicament while maintaining a sealed interface. In addition, a vial adapter (380) for engaging a filling station (284) to fill a fluid delivery device (210).
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公开(公告)号:US20240269378A1
公开(公告)日:2024-08-15
申请号:US18567616
申请日:2022-06-07
Applicant: Becton, Dickinson and Company
Inventor: Eric SUN , Richard J. GYORY , Mark WOOD , Dana COTE , Tieying JIANG , Alessandro PIZZOCHERO , Randy MOSHER
CPC classification number: A61M5/14566 , A61M5/14248 , A61M39/22 , A61M2205/3331 , A61M2205/3368
Abstract: Disclosed is a medication delivery system comprising: a container for a medium: a plunger disposed in the container; and a lead screw axially fixed with respect to the container and in threaded engagement with the plunger, where the lead screw is disposed inside of the container, and the rotation of the lead screw causes axial displacement of the plunger with respect to the container. A patch pump comprising the medication delivery system and a medicament delivery device comprising the medication delivery system are also disclosed.
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