公开(公告)号：US20230272454A1

公开(公告)日：2023-08-31

申请号：US18190465

申请日：2023-03-27

Applicant: Becton, Dickinson and Company

Inventor： Devon Jensen ,  Katherine Lazaruk ,  Dennis Prosen ,  Ricelle A. Acob ,  Kai Liu

IPC: C12Q1/6806 ,  C07K14/705 ,  C07K14/725 ,  C12Q1/6858

CPC classification number: C12Q1/6806 ,  C07K14/70503 ,  C07K14/7051 ,  C12Q1/6858

Abstract: Disclosed herein include systems, methods, compositions, and kits for immune repertoire profiling. There are provided, in some embodiments, primer panels enabling the determination of the nucleotide sequence of the complete variable region of nucleic acids encoding mouse B cell receptor (BCR) and T cell receptor (TCR) polypeptides. In some embodiments, the method comprises single cell transcriptomic analysis.

公开(公告)号：US11661625B2

公开(公告)日：2023-05-30

申请号：US17320052

申请日：2021-05-13

Applicant: Becton, Dickinson and Company

Inventor： Devon Jensen ,  Katherine Lazaruk ,  Dennis Prosen ,  Ricelle A. Acob ,  Kai Liu

IPC: C12Q1/68 ,  C12Q1/6806 ,  C07K14/705 ,  C07K14/725 ,  C12Q1/6858

CPC classification number: C12Q1/6806 ,  C07K14/7051 ,  C07K14/70503 ,  C12Q1/6858

Abstract: Disclosed herein include systems, methods, compositions, and kits for immune repertoire profiling. There are provided, in some embodiments, primer panels enabling the determination of the nucleotide sequence of the complete variable region of nucleic acids encoding mouse B cell receptor (BCR) and T cell receptor (TCR) polypeptides. In some embodiments, the method comprises single cell transcriptomic analysis.

公开(公告)号：US20210355484A1

公开(公告)日：2021-11-18

申请号：US17320052

申请日：2021-05-13

Applicant: Becton, Dickinson and Company

Inventor： Devon Jensen ,  Katherine Lazaruk ,  Dennis Prosen ,  Ricelle A. Acob ,  Kai Liu

IPC: C12N15/10 ,  C12Q1/6858 ,  C07K14/705 ,  C07K14/725

Abstract: Disclosed herein include systems, methods, compositions, and kits for immune repertoire profiling. There are provided, in some embodiments, primer panels enabling the determination of the nucleotide sequence of the complete variable region of nucleic acids encoding mouse B cell receptor (BCR) and T cell receptor (TCR) polypeptides. In some embodiments, the method comprises single cell transcriptomic analysis.