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公开(公告)号：US20150210684A1
公开(公告)日：2015-07-30
申请号：US14419559
申请日：2013-08-07
发明人： Tao Wang , Zhongxing Zhang , John F. Kadow , Nicholas A. Meanwell , Edward H. Ruediger , Clint A. James , Daniel H. Deon , David J. Carini , Barry L. Johnson
IPC分类号： C07D471/04 , A61K45/06 , A61K31/4545 , C07D401/06 , A61K31/454
CPC分类号： C07D471/04 , A61K31/454 , A61K31/4545 , A61K45/06 , C07D401/06
摘要： Compounds of Formula I, including pharmaceutically acceptable salts thereof: formule (I): wherein A is selected from the group consisting of: formule (II) and wherein Z is selected from the group consisting of: formule (III): and. are useful as HIV attachment inhibitors.
摘要翻译： 式I化合物，包括其药学上可接受的盐：式（I）：其中A选自：结构（II），并且其中Z选自：基团（III）：和。 可用作HIV附着抑制剂。
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2.发明申请PIPERAZINE AND HOMOPIPERAZINE DERIVATIVES AS HIV ATTACHMENT INHIBITORS 审中-公开作为艾滋病毒药物抑制剂的哌嗪和异丙肾上腺素衍生物公开(公告)号：US20160052923A1
公开(公告)日：2016-02-25
申请号：US14779638
申请日：2014-03-25
发明人： Tao Wang , Zhiwei Yin , Zhongxing Zhang , Barry L. Johnson , John F. Kadow , Nicholas A. Meanwell
IPC分类号： C07D471/04 , A61K45/06 , A61K31/519 , A61K31/496 , A61K31/551
CPC分类号： C07D471/04 , A61K31/496 , A61K31/519 , A61K31/551 , A61K45/06 , C07D519/00
摘要： Compounds of Formula I, including pharmaceutically acceptable salts thereof, are useful as HIV attachment inhibitors.
摘要翻译： 式I化合物，包括其药学上可接受的盐，可用作HIV附着抑制剂。
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公开(公告)号：US09505752B2
公开(公告)日：2016-11-29
申请号：US14419559
申请日：2013-08-07
发明人： Tao Wang , Zhongxing Zhang , John F. Kadow , Nicholas A. Meanwell , Edward H. Ruediger , Clint A. James , Daniel H. Deon , David J. Carini , Barry L. Johnson
IPC分类号： C07D471/04 , A61K31/4545 , C07D401/06 , A61K31/454 , A61K45/06
CPC分类号： C07D471/04 , A61K31/454 , A61K31/4545 , A61K45/06 , C07D401/06
摘要： Compounds of Formula I, including pharmaceutically acceptable salts thereof: formula (I): wherein A is selected from the group consisting of: formula (II) and wherein Z is selected from the group consisting of: formula (III): and. are useful as HIV attachment inhibitors.
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公开(公告)号：US20160052924A1
公开(公告)日：2016-02-25
申请号：US14779648
申请日：2014-03-25
发明人： Tao Wang , Zhiwei Yin , Zhongxing Madison , John A. Bender , Barry L. Johnson , Jhon F. Kadow , Nicholas A. Meanwell
IPC分类号： C07D471/04 , A61K31/4545 , A61K45/06 , C07D401/06 , A61K31/454 , A61K31/437 , A61K31/55
CPC分类号： C07D471/04 , A61K31/437 , A61K31/454 , A61K31/4545 , A61K31/55 , A61K45/06 , C07D401/06 , C07D519/00
摘要： Compounds of Formula I, including pharmaceutically acceptable salts thereof: I useful as HIV attachment inhibitors.
摘要翻译： 式I的化合物，包括其药学上可接受的盐：可用作HIV附着抑制剂。
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公开(公告)号：US20130210857A1
公开(公告)日：2013-08-15
申请号：US13766587
申请日：2013-02-13
发明人： Michael A. Walker , Margaret E. Sorenson , B. Narasimhulu Naidu , Kevin Peese , Barry L. Johnson , Manoj Patel
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , A61K31/4375
摘要： The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
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公开(公告)号：US08629276B2
公开(公告)日：2014-01-14
申请号：US13766587
申请日：2013-02-13
发明人： Michael A. Walker , Margaret E. Sorenson , B. Narasimhulu Naidu , Kevin Peese , Barry L. Johnson , Manoj Patel
IPC分类号： A61K31/44 , C07D471/02
CPC分类号： C07D471/04 , A61K31/4375
摘要： The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
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