公开(公告)号：US20240308954A1

公开(公告)日：2024-09-19

申请号：US18549986

申请日：2022-03-11

Applicant: BIOMEDCODE HELLAS SA

Inventor： George Kollias ,  Niki Karagianni ,  Maria C. Denis ,  Alexios N. Matralis ,  Dimitra Papadopoulou ,  Eleni Karkoulia

IPC: C07C237/44 ,  A61K31/166 ,  A61K31/353 ,  A61K31/44 ,  A61K31/4418 ,  A61K31/451 ,  A61K31/495 ,  A61K31/5375 ,  A61K31/5377 ,  A61K31/54 ,  A61P29/00 ,  C07C231/02 ,  C07D211/38 ,  C07D213/40 ,  C07D213/82 ,  C07D241/44 ,  C07D295/135 ,  C07D311/58 ,  C07D471/04

CPC classification number: C07C237/44 ,  A61K31/166 ,  A61K31/353 ,  A61K31/44 ,  A61K31/4418 ,  A61K31/451 ,  A61K31/495 ,  A61K31/5375 ,  A61K31/5377 ,  A61K31/54 ,  A61P29/00 ,  C07C231/02 ,  C07D211/38 ,  C07D213/40 ,  C07D213/82 ,  C07D241/44 ,  C07D295/135 ,  C07D311/58 ,  C07D471/04 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2601/18

Abstract: A compound of formula (I) or a pharmaceutically acceptable salt, hydrate, or isomer thereof. Pharmaceutical compositions comprising the compounds of formula (I) as well as their use in therapy, particularly in the treatment of inflammatory conditions. Advantageously, the compounds show a broad and robust anti-inflammatory effect, and are therapeutically safe.