公开(公告)号：US20230270890A1

公开(公告)日：2023-08-31

申请号：US18073624

申请日：2022-12-02

Applicant: BIOACTS CORPORATION

Inventor： JIN WOO PARK ,  SU JUNG JANG ,  EUNAE JEONG ,  JIHYUN LEE ,  KIWON KIM ,  EUNSEO YU ,  NURI CHOI ,  GYEONG RIM SHIN

IPC: A61K49/00

CPC classification number: A61K49/0032

Abstract: Provided is a fluorescent compound for labeling a biomaterial having the following Chemical Formula 1:




In Chemical Formula 1 above,



X1 and X2 are the same as or different from each other, and each independently selected from H, —SO3− and SO3H,
R1 and R2 are the same as each other or each independently selected from C1-7 alkyl, C8-18 alkyl, —(CH2)mSO3−, —(CH2)mSO3H, and










R3 and R4 are the same as or different from each other and each independently selected from C1-7 alkyl, —(CH2)mCOOZ and










R3 and R4 are simultaneously not any one selected from —(CH2)mCOOZ and

公开(公告)号：US20230273192A1

公开(公告)日：2023-08-31

申请号：US18073631

申请日：2022-12-02

Applicant: BIOACTS CORPORATION

Inventor： JIN WOO PARK ,  KIWON KIM ,  SU JUNG JANG ,  NURI CHOI ,  GYEONG RIM SHIN

IPC: G01N33/533 ,  C07D405/14 ,  C07D405/12 ,  C07D491/153

CPC classification number: G01N33/533 ,  C07D405/12 ,  C07D405/14 ,  C07D491/153

Abstract: Provided is a fluorescent compound for detecting a biomaterial having the following Chemical Formula 1:





In Chemical Formula 1 above,

R1 and R5 are the same as or different from each other, and each independently selected from H, —SO3- and SO3H,
R2 and R6 are the same as each other or each independently selected from hydrogen or methyl
R4 and R8 are the same as or different from each other, and each independently selected from H, —SO3- and (CH2)SO3H,
R3 and R4 can form alkylene chain with arbituary-substituted 3 carbons combined with the nitrogen atom attached with R3,
R7 and R8 can form alkylene chain with arbituary-substituted 3 carbons combined with the nitrogen atom attached with R7,
when R8 and R8 do not form alkylene chain, R6, R7 and R8 are hydrogen at the same time and the nitrogen atom attached with R6 and R7 at the same time forms double bond with the carbon of mother molecule and has positive charge.