公开(公告)号：US20230271968A1

公开(公告)日：2023-08-31

申请号：US18016164

申请日：2021-07-13

Applicant: BEIJING TIDE PHARMACEUTICAL CO., LTD.

Inventor： Cheung Ling Cheng ,  Yanping Zhao ,  Hongjun Wang ,  Bin Liu ,  Weiting Zhong ,  Huifen Xu ,  Chuangchuang Huang ,  Jing Li ,  Weina Liu

IPC: C07D487/04 ,  A61P35/00

CPC classification number: C07D487/04 ,  A61P35/00

Abstract: Disclosed is a compound of a general formula (I), which may be used for the treatment of ATR kinase-mediated diseases, for example, proliferative diseases such as cancer. Further disclosed are a preparation method for the compound of the general formula (I), a pharmaceutical composition, and use of the pharmaceutical composition for the treatment of ATR kinase-mediated diseases.